hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_03841.1
Complex Portal: CPX-15430
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PYGO2 | Pygopus homolog 2 | 5 | UniProt NCBI |
| BCL9L | B-cell CLL/lymphoma 9-like protein (B-cell lymphoma 9-like protein) (BCL9-like protein) (Protein BCL9-2) | 5 | UniProt NCBI |
| ZMIZ1 | Zinc finger MIZ domain-containing protein 1 (PIAS-like protein Zimp10) (Retinoic acid-induced protein 17) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-3769402 | 0.00428896488724 | 0.666666666667 | PYGO2 BCL9L | Deactivation of the beta-catenin transactivating complex |
| REAC:R-HSA-201722 | 0.019882541548 | 0.666666666667 | PYGO2 BCL9L | Formation of the beta-catenin:TCF transactivating complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| BCL9L | ZMIZ1 | 0.977 | 0.076 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| PYGO2 | BCL9L | 0.974 | 0.076 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| PYGO2 | ZMIZ1 | 0.415 | 0.1 | bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| PYGO2 | huMAP3_03841.1 |
| BCL9L | huMAP3_03841.1 huMAP3_06734.1 huMAP3_08488.1 |
| ZMIZ1 | huMAP3_03841.1 huMAP3_08488.1 |