hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_03846.1
Complex Portal: CPX-16257
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MPO | Myeloperoxidase (MPO) (EC 1.11.2.2) [Cleaved into: Myeloperoxidase; 89 kDa myeloperoxidase; 84 kDa myeloperoxidase; Myeloperoxidase light chain; Myeloperoxidase heavy chain] | 5 | UniProt NCBI |
| CTSG | Cathepsin G (CG) (EC 3.4.21.20) [Cleaved into: Cathepsin G, C-terminal truncated form] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04613 | 0.00179249345126 | 1.0 | MPO CTSG | Neutrophil extracellular trap formation |
| WP:WP4818 | 0.0310970405539 | 0.5 | CTSG | Conversion of angiotensinogen to angiotensin II |
| WP:WP3891 | 0.0373151717536 | 0.5 | MPO | Benzene metabolism |
| KEGG:04614 | 0.0474849820587 | 0.5 | CTSG | Renin-angiotensin system |
| REAC:R-HSA-8941413 | 0.0499419797295 | 0.5 | MPO | Events associated with phagocytolytic activity of PMN cells |
| CORUM:5389 | 0.0499419797295 | 0.5 | CTSG | SERPINA3-CTSG complex |
| CORUM:5391 | 0.0499419797295 | 0.5 | CTSG | SERPINA1-CTSG complex |
| CORUM:6825 | 0.0499419797295 | 0.5 | MPO | CP-MPO complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| MPO | CTSG | 0.956 | 0.328 | bioplex_WMM bioplex3_WMM WMM_only treiber_WMM |
Related Complexes
| Genename | Complexes |
|---|---|
| MPO | huMAP3_03846.1 huMAP3_10260.1 huMAP3_11343.1 huMAP3_13546.1 |
| CTSG | huMAP3_03846.1 huMAP3_10260.1 huMAP3_11343.1 huMAP3_13546.1 |