hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_03858.1
Confidence: Extremely High  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
SLC9A6 | Sodium/hydrogen exchanger 6 (Na(+)/H(+) exchanger 6) (NHE-6) (Solute carrier family 9 member 6) | 5 | UniProt   NCBI |
SLC9A7 | Sodium/hydrogen exchanger 7 (Na(+)/H(+) exchanger 7) (NHE-7) (Solute carrier family 9 member 7) | 5 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  REAC:R-HSA-425986 | 3.58839967947e-05 | 1.0 | SLC9A7 SLC9A6 | Sodium/Proton exchangers |
  KEGG:04260 | 0.000415528139074 | 1.0 | SLC9A7 SLC9A6 | Cardiac muscle contraction |
  REAC:R-HSA-425393 | 0.00344486369229 | 1.0 | SLC9A7 SLC9A6 | Transport of inorganic cations/anions and amino acids/oligopeptides |
  GO:0015386 | 0.00983221512175 | 1.0 | SLC9A7 SLC9A6 | potassium:proton antiporter activity |
  HP:0002307 | 0.0159119894358 | 1.0 | SLC9A7 SLC9A6 | Drooling |
  GO:0015385 | 0.016855225923 | 1.0 | SLC9A7 SLC9A6 | sodium:proton antiporter activity |
  GO:0022821 | 0.016855225923 | 1.0 | SLC9A7 SLC9A6 | solute:potassium antiporter activity |
  HP:0003781 | 0.0186596783332 | 1.0 | SLC9A7 SLC9A6 | Excessive salivation |
  REAC:R-HSA-425407 | 0.0217354494871 | 1.0 | SLC9A7 SLC9A6 | SLC-mediated transmembrane transport |
  REAC:R-HSA-5619092 | 0.0249718442457 | 0.5 | SLC9A6 | Defective SLC9A6 causes X-linked, syndromic mental retardation,, Christianson type (MRXSCH) |
  HP:0001419 | 0.0356789453845 | 1.0 | SLC9A7 SLC9A6 | X-linked recessive inheritance |
  GO:0051139 | 0.0426062655276 | 1.0 | SLC9A7 SLC9A6 | metal cation:proton antiporter activity |
  GO:0098719 | 0.0491610756088 | 1.0 | SLC9A7 SLC9A6 | sodium ion import across plasma membrane |
  HP:0100755 | 0.0496737041344 | 1.0 | SLC9A7 SLC9A6 | Abnormality of salivation |
  HP:0006794 | 0.0499436884913 | 0.5 | SLC9A6 | Loss of ability to walk in first decade |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
---|---|---|---|---|
 SLC9A6 |  SLC9A7 | 0.999 |            | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116     |
Related Complexes
Genename | Complexes |
---|---|
SLC9A6 | huMAP3_02201.1 huMAP3_03858.1 huMAP3_10848.1 huMAP3_11004.1 huMAP3_11349.1 |
SLC9A7 | huMAP3_03858.1 huMAP3_11004.1 huMAP3_11349.1 |