hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_03894.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GSPT1 | Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (Eukaryotic peptide chain release factor subunit 3a) (eRF3a) (EC 3.6.5.-) (G1 to S phase transition protein 1 homolog) | 5 | UniProt NCBI |
| ETF1 | Eukaryotic peptide chain release factor subunit 1 (Eukaryotic release factor 1) (eRF1) (Protein Cl1) (TB3-1) | 5 | UniProt NCBI |
| FEN1 | Flap endonuclease 1 (FEN-1) (EC 3.1.-.-) (DNase IV) (Flap structure-specific endonuclease 1) (Maturation factor 1) (MF1) (hFEN-1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:809 | 0.0249718442457 | 0.5 | ETF1 | eRF1-eRF3-GTP-Mg(2+) complex |
| KEGG:03450 | 0.0261247873322 | 0.5 | FEN1 | Non-homologous end-joining |
| CORUM:7282 | 0.0499419797295 | 0.5 | FEN1 | FEN1-WRN complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| ETF1 | GSPT1 | 0.983 | 0.648 | hein_WMM youn () bioplex_WMM bioplex3_WMM youn_WMM hein () gupta_WMM |
| ETF1 | FEN1 | 0.965 | 0.178 | youn () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| FEN1 | GSPT1 | 0.002 | 0.352 | youn_WMM gupta_WMM fraction bioplex_WMM |
Related Complexes