hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_03918.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| VPS37D | Vacuolar protein sorting-associated protein 37D (ESCRT-I complex subunit VPS37D) (Williams-Beuren syndrome chromosomal region 24 protein) | 5 | UniProt NCBI |
| P3H2 | Prolyl 3-hydroxylase 2 (EC 1.14.11.7) (Leprecan-like protein 1) (Myxoid liposarcoma-associated protein 4) | 5 | UniProt NCBI |
| TOR4A | Torsin-4A (Torsin family 4 member A) | 3 | UniProt NCBI |
| P3H1 | Prolyl 3-hydroxylase 1 (EC 1.14.11.7) (Growth suppressor 1) (Leucine- and proline-enriched proteoglycan 1) (Leprecan-1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4786 | 0.0011843872874 | 0.5 | P3H2 P3H1 | Type I collagen synthesis in the context of osteogenesis imperfecta |
| GO:0019797 | 0.00842684400117 | 0.5 | P3H2 P3H1 | procollagen-proline 3-dioxygenase activity |
| REAC:R-HSA-1650814 | 0.0135329645116 | 0.5 | P3H2 P3H1 | Collagen biosynthesis and modifying enzymes |
| GO:0031544 | 0.0168521501606 | 0.5 | P3H2 P3H1 | peptidyl-proline 3-dioxygenase activity |
| REAC:R-HSA-1474290 | 0.0260384914588 | 0.5 | P3H2 P3H1 | Collagen formation |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| P3H2 | P3H1 | 0.998 | 0.018 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only |
| P3H1 | VPS37D | 0.983 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| TOR4A | P3H1 | 0.96 | 0.058 | bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes