hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_03944.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GATC | Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial (Glu-AdT subunit C) (EC 6.3.5.-) (Protein 15E1.2) | 5 | UniProt NCBI |
| QRSL1 | Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial (Glu-AdT subunit A) (EC 6.3.5.7) (Glutaminyl-tRNA synthase-like protein 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6959 | 5.12628525639e-06 | 1.0 | GATC QRSL1 | GATB-GATC-QRSL1 complex |
| KEGG:00970 | 0.000146800434109 | 1.0 | GATC QRSL1 | Aminoacyl-tRNA biosynthesis |
| HP:0008163 | 0.00111069513888 | 1.0 | GATC QRSL1 | Decreased circulating cortisol level |
| GO:0050567 | 0.00140460216025 | 1.0 | GATC QRSL1 | glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity |
| GO:0030956 | 0.00140460216025 | 1.0 | GATC QRSL1 | glutamyl-tRNA(Gln) amidotransferase complex |
| GO:0070681 | 0.00140460216025 | 1.0 | GATC QRSL1 | glutaminyl-tRNAGln biosynthesis via transamidation |
| HP:0011924 | 0.00240251902349 | 1.0 | GATC QRSL1 | Decreased activity of mitochondrial complex III |
| HP:0008207 | 0.00353713682691 | 1.0 | GATC QRSL1 | Primary adrenal insufficiency |
| HP:0011731 | 0.00401900764101 | 1.0 | GATC QRSL1 | Abnormality of circulating cortisol level |
| HP:0012111 | 0.00418646629272 | 1.0 | GATC QRSL1 | Abnormality of circulating glucocorticoid level |
| HP:0008347 | 0.00507502240382 | 1.0 | GATC QRSL1 | Decreased activity of mitochondrial complex IV |
| HP:0001790 | 0.00584738271579 | 1.0 | GATC QRSL1 | Nonimmune hydrops fetalis |
| HP:0000846 | 0.00973994198714 | 1.0 | GATC QRSL1 | Adrenal insufficiency |
| HP:0003811 | 0.0113495955576 | 1.0 | GATC QRSL1 | Neonatal death |
| HP:0011923 | 0.0133830220427 | 1.0 | GATC QRSL1 | Decreased activity of mitochondrial complex I |
| GO:0016884 | 0.016855225923 | 1.0 | GATC QRSL1 | carbon-nitrogen ligase activity, with glutamine as amido-N-donor |
| HP:0011733 | 0.0179522509679 | 1.0 | GATC QRSL1 | Abnormality of adrenal physiology |
| HP:0001789 | 0.0201155433461 | 1.0 | GATC QRSL1 | Hydrops fetalis |
| HP:0008972 | 0.0277776310426 | 1.0 | GATC QRSL1 | Decreased activity of mitochondrial respiratory chain |
| HP:0011922 | 0.0295479082178 | 1.0 | GATC QRSL1 | Abnormal activity of mitochondrial respiratory chain |
| HP:0001622 | 0.0346981161387 | 1.0 | GATC QRSL1 | Premature birth |
| HP:0000834 | 0.0490927251387 | 1.0 | GATC QRSL1 | Abnormality of the adrenal glands |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| GATC | QRSL1 | 1.0 | 0.68 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
Related Complexes