hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_03957.1
Complex Portal: CPX-17219
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ST14 | Suppressor of tumorigenicity 14 protein (EC 3.4.21.109) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease 14) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein) | 5 | UniProt NCBI |
| IL6ST | Interleukin-6 receptor subunit beta (IL-6 receptor subunit beta) (IL-6R subunit beta) (IL-6R-beta) (IL-6RB) (CDw130) (Interleukin-6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin-M receptor subunit alpha) (CD antigen CD130) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0000966 | 0.00604901660254 | 1.0 | ST14 IL6ST | Hypohidrosis |
| HP:0000989 | 0.020488053408 | 1.0 | ST14 IL6ST | Pruritus |
| CORUM:3229 | 0.0499419797295 | 0.5 | IL6ST | CDK9-IL6ST complex |
| CORUM:5579 | 0.0499419797295 | 0.5 | IL6ST | CNTF-CNTFR-gp130-LIFR complex |
| CORUM:5582 | 0.0499419797295 | 0.5 | IL6ST | LIFR-LIF-gp130 complex |
| HP:0011082 | 0.0499436884913 | 0.5 | ST14 | Conical primary incisor |
| HP:0025419 | 0.0499436884913 | 0.5 | IL6ST | Pulmonary pneumatocele |
| HP:0033332 | 0.0499436884913 | 0.5 | IL6ST | Elevated circulating amyloid A |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| IL6ST | ST14 | 0.959 | 0.056 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes