hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_03960.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| BUB1 | Mitotic checkpoint serine/threonine-protein kinase BUB1 (hBUB1) (EC 2.7.11.1) (BUB1A) | 5 | UniProt NCBI |
| BUB3 | Mitotic checkpoint protein BUB3 | 5 | UniProt NCBI |
| ZNF207 | BUB3-interacting and GLEBS motif-containing protein ZNF207 (BuGZ) (hBuGZ) (Zinc finger protein 207) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1851 | 3.41752350426e-06 | 0.666666666667 | BUB1 BUB3 | BUB1-BUB3 complex |
| WP:WP4240 | 0.000103023242897 | 0.666666666667 | BUB1 BUB3 | Regulation of sister chromatid separation at the metaphase anaphase transition |
| HP:0100650 | 0.000569225481094 | 0.666666666667 | BUB1 BUB3 | Vaginal neoplasm |
| GO:0071173 | 0.00102463963787 | 1.0 | ZNF207 BUB3 BUB1 | spindle assembly checkpoint signaling |
| GO:0007094 | 0.00102463963787 | 1.0 | ZNF207 BUB3 BUB1 | mitotic spindle assembly checkpoint signaling |
| GO:0071174 | 0.00102463963787 | 1.0 | ZNF207 BUB3 BUB1 | mitotic spindle checkpoint signaling |
| GO:2000816 | 0.00110345807156 | 1.0 | ZNF207 BUB3 BUB1 | negative regulation of mitotic sister chromatid separation |
| GO:0031577 | 0.00110345807156 | 1.0 | ZNF207 BUB3 BUB1 | spindle checkpoint signaling |
| GO:0033046 | 0.00110345807156 | 1.0 | ZNF207 BUB3 BUB1 | negative regulation of sister chromatid segregation |
| GO:0033048 | 0.00110345807156 | 1.0 | ZNF207 BUB3 BUB1 | negative regulation of mitotic sister chromatid segregation |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| BUB1 | BUB3 | 0.999 | 0.34 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 |
| ZNF207 | BUB3 | 0.994 | 0.925333333333 | bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM fraction boldt_WMM |
| ZNF207 | BUB1 | 0.981 | 0.16 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| ZNF207 | huMAP3_03960.1 huMAP3_12747.1 |
| BUB1 | huMAP3_03960.1 huMAP3_11940.1 |
| BUB3 | huMAP3_03960.1 huMAP3_12747.1 |