hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_03964.1
Confidence: Extremely High  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
CYP8B1 | 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase (EC 1.14.14.139) (7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase) (CYPVIIIB1) (Cytochrome P450 8B1) (Sterol 12-alpha-hydroxylase) | 5 | UniProt   NCBI |
TACSTD2 | Tumor-associated calcium signal transducer 2 (Cell surface glycoprotein Trop-2) (Membrane component chromosome 1 surface marker 1) (Pancreatic carcinoma marker protein GA733-1) | 5 | UniProt   NCBI |
UNC5C | Netrin receptor UNC5C (Protein unc-5 homolog 3) (Protein unc-5 homolog C) | 5 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  KEGG:00120 | 0.0334562504346 | 0.333333333333 | CYP8B1 | Primary bile acid biosynthesis |
  REAC:R-HSA-211994 | 0.0498224659464 | 0.333333333333 | CYP8B1 | Sterols are 12-hydroxylated by CYP8B1 |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
---|---|---|---|---|
 CYP8B1 |  TACSTD2 | 0.99 |            | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     |
 TACSTD2 |  UNC5C | 0.952 |            | bioplex3_HEK293     bioplex3_WMM     WMM_only     |
Related Complexes
Genename | Complexes |
---|---|
CYP8B1 | huMAP3_03964.1 huMAP3_08650.1 huMAP3_11434.1 huMAP3_14095.1 |
TACSTD2 | huMAP3_03964.1 huMAP3_08650.1 huMAP3_14095.1 |
UNC5C | huMAP3_03964.1 huMAP3_14095.1 |