hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_03990.1
Complex Portal: CPX-14689
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| C22orf15 | Uncharacterized protein C22orf15 (Protein N27C7-3) | 4 | UniProt NCBI |
| ZBTB16 | Zinc finger and BTB domain-containing protein 16 (Promyelocytic leukemia zinc finger protein) (Zinc finger protein 145) (Zinc finger protein PLZF) | 5 | UniProt NCBI |
| WIPI2 | WD repeat domain phosphoinositide-interacting protein 2 (WIPI-2) (WIPI49-like protein 2) | 5 | UniProt NCBI |
| BCAS3 | BCAS3 microtubule associated cell migration factor (Breast carcinoma-amplified sequence 3) (GAOB1) | 5 | UniProt NCBI |
| PHAF1 | Phagosome assembly factor 1 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0000407 | 0.00475337188383 | 0.6 | BCAS3 WIPI2 PHAF1 | phagophore assembly site |
| WP:WP2858 | 0.0379631029161 | 0.4 | BCAS3 ZBTB16 | Ectoderm differentiation |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PHAF1 | BCAS3 | 1.0 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM boldt_WMM | |
| BCAS3 | WIPI2 | 0.999 |
mutually_exclusive (Q9BSU1)
structurally_consistent (dimer) |
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 gupta_WMM fraction | |
| PHAF1 | WIPI2 | 0.998 | 0.108 |
mutually_exclusive (Q9H6U6)
structurally_consistent (dimer) |
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM |
| ZBTB16 | PHAF1 | 0.985 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| C22orf15 | PHAF1 | 0.979 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| C22orf15 | BCAS3 | 0.744 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| ZBTB16 | BCAS3 | 0.168 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes