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hu.MAP 3.0
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hu.MAP 3.0: Complex View
Human Protein Complex Map
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List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):
Enrichment (ex. cilium):
Protein (ex. Centrosomal protein):
Complex:
huMAP3_03995.1
Complex Portal:
CPX-13506
Confidence:
Extremely High
?
Proteins
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Genename
Protein Name
Uniprot Annotation Score
Links
DUSP16
Dual specificity protein phosphatase 16 (EC 3.1.3.16) (EC 3.1.3.48) (Mitogen-activated protein kinase phosphatase 7) (MAP kinase phosphatase 7) (MKP-7)
5
UniProt
NCBI
MAPK14
Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAP kinase MXI2) (MAX-interacting protein 2) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) (SAPK2a)
5
UniProt
NCBI
MKNK1
MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (MAPK signal-integrating kinase 1) (Mnk1)
5
UniProt
NCBI
MKNK2
MAP kinase-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 2) (MAPK signal-integrating kinase 2) (Mnk2)
5
UniProt
NCBI
Showing 1 to 4 of 4 entries
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Enrichments
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Term ID
Corrected Pval
Fraction Complex Coverage
Proteins
Term Name
WP:WP382
1.5787183916e-06
1.0
MAPK14 DUSP16 MKNK1 MKNK2
MAPK signaling pathway
KEGG:04010
3.32954535329e-06
1.0
MAPK14 DUSP16 MKNK1 MKNK2
MAPK signaling pathway
WP:WP2637
4.30466180211e-06
0.75
MAPK14 MKNK1 MKNK2
Interleukin 1 IL 1 structural pathway
WP:WP3879
0.000535373329556
0.5
MKNK1 MKNK2
4 hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression
WP:WP400
0.00110807642161
0.5
MKNK1 MAPK14
p38 MAPK signaling pathway
WP:WP5087
0.0029183957539
0.75
MAPK14 MKNK1 MKNK2
Pleural mesothelioma
KEGG:04066
0.0120599434394
0.5
MKNK1 MKNK2
HIF-1 signaling pathway
KEGG:04148
0.0189154103852
0.5
DUSP16 MAPK14
Efferocytosis
KEGG:04910
0.0195294442288
0.5
MKNK1 MKNK2
Insulin signaling pathway
GO:0048273
0.0280843539964
0.5
DUSP16 MAPK14
mitogen-activated protein kinase p38 binding
Showing 1 to 10 of 10 entries
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Edges
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Protein 1
Protein 2
Score
?
ProteomeHD
?
Interface Overlap
?
Evidence
?
MAPK14
MKNK1
0.999
0.154
structurally_consistent (dimer)
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
MAPK14
DUSP16
0.986
structurally_consistent (dimer)
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
MKNK2
MAPK14
0.975
structurally_consistent (dimer)
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
MKNK2
MKNK1
0.551
mutually_exclusive (Q16539)
bioplex_WMM bioplex3_WMM WMM_only
MKNK2
DUSP16
0.498
mutually_exclusive (Q16539)
bioplex_WMM bioplex3_WMM WMM_only
DUSP16
MKNK1
0.214
mutually_exclusive (Q16539)
bioplex_WMM bioplex3_WMM WMM_only
Showing 1 to 6 of 6 entries
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Related Complexes
Genename
Complexes
MKNK1
huMAP3_01628.1
huMAP3_03995.1
huMAP3_05402.1
huMAP3_06585.1
huMAP3_07439.1
huMAP3_07936.1
huMAP3_08665.1
huMAP3_10997.1
huMAP3_13620.1
huMAP3_14776.1
MKNK2
huMAP3_01311.1
huMAP3_01628.1
huMAP3_03995.1
huMAP3_05402.1
huMAP3_06585.1
huMAP3_07439.1
huMAP3_07582.1
huMAP3_07936.1
huMAP3_08665.1
huMAP3_10997.1
huMAP3_13413.1
huMAP3_14776.1
DUSP16
huMAP3_01628.1
huMAP3_03995.1
huMAP3_05402.1
huMAP3_06585.1
huMAP3_07439.1
huMAP3_07936.1
huMAP3_08665.1
huMAP3_10997.1
huMAP3_12478.1
MAPK14
huMAP3_01628.1
huMAP3_03995.1
huMAP3_05402.1
huMAP3_06585.1
huMAP3_07439.1
huMAP3_07936.1
huMAP3_08665.1
huMAP3_10997.1
huMAP3_14776.1