hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_04010.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PTGR2 | Prostaglandin reductase 2 (PRG-2) (EC 1.3.1.48) (15-oxoprostaglandin 13-reductase) (Zinc-binding alcohol dehydrogenase domain-containing protein 1) | 5 | UniProt NCBI |
| FASN | Fatty acid synthase (EC 2.3.1.85) (Type I fatty acid synthase) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Acyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-8978868 | 0.0180872431463 | 1.0 | FASN PTGR2 | Fatty acid metabolism |
| KEGG:00061 | 0.0356198329076 | 0.5 | FASN | Fatty acid biosynthesis |
| WP:WP2874 | 0.049750157242 | 0.5 | FASN | Liver X receptor pathway |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| FASN | PTGR2 | 0.983 | 0.134 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
Related Complexes
| Genename | Complexes |
|---|---|
| PTGR2 | huMAP3_00676.1 huMAP3_01662.1 huMAP3_04010.1 huMAP3_04810.1 huMAP3_10103.1 |
| FASN | huMAP3_00676.1 huMAP3_01662.1 huMAP3_03291.1 huMAP3_04010.1 huMAP3_04810.1 huMAP3_10103.1 |