hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_04016.1
Complex Portal: CPX-15434
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SOX2 | Transcription factor SOX-2 | 5 | UniProt NCBI |
| SOX21 | Transcription factor SOX-21 (SOX-A) | 3 | UniProt NCBI |
| SOX14 | Transcription factor SOX-14 (Protein SOX-28) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP2853 | 0.00738685655077 | 0.666666666667 | SOX21 SOX2 | Endoderm differentiation |
| WP:WP2857 | 0.00901139826353 | 0.666666666667 | SOX21 SOX2 | Mesodermal commitment pathway |
| CORUM:2802 | 0.0249718442456 | 0.333333333333 | SOX2 | OCT1-SOX2 DNA-protein complex |
| CORUM:2803 | 0.0249718442456 | 0.333333333333 | SOX2 | PAX6-SOX2 DNA-protein complex |
| WP:WP3299 | 0.0413734636003 | 0.333333333333 | SOX2 | let 7 inhibition of ES cell reprogramming |
| CORUM:2801 | 0.0499402709677 | 0.333333333333 | SOX2 | OCT4-SOX2 DNA-protein complex |
| CORUM:7102 | 0.0499402709677 | 0.333333333333 | SOX2 | SOX2-VRK1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| SOX2 | SOX21 | 0.995 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| SOX2 | SOX14 | 0.993 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| SOX21 | SOX14 | 0.568 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| SOX2 | huMAP3_04016.1 huMAP3_14421.1 |
| SOX21 | huMAP3_04016.1 huMAP3_14421.1 |
| SOX14 | huMAP3_04016.1 huMAP3_14421.1 huMAP3_15053.1 huMAP3_15274.1 |