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hu.MAP 3.0
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hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):
Enrichment (ex. cilium):
Protein (ex. Centrosomal protein):
Complex:
huMAP3_04028.1
Confidence:
Extremely High
?
Proteins
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Genename
Protein Name
Uniprot Annotation Score
Links
CCNI
Cyclin-I
4
UniProt
NCBI
CDK5
Cyclin-dependent kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) (Cyclin-dependent-like kinase 5) (Serine/threonine-protein kinase PSSALRE) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit)
5
UniProt
NCBI
CDK5R1
Cyclin-dependent kinase 5 activator 1 (CDK5 activator 1) (Cyclin-dependent kinase 5 regulatory subunit 1) (TPKII regulatory subunit) [Cleaved into: Cyclin-dependent kinase 5 activator 1, p35 (p35); Cyclin-dependent kinase 5 activator 1, p25 (p25) (Tau protein kinase II 23 kDa subunit) (p23)]
5
UniProt
NCBI
Showing 1 to 3 of 3 entries
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Enrichments
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Term ID
Corrected Pval
Fraction Complex Coverage
Proteins
Term Name
REAC:R-HSA-9032845
6.81752388431e-05
0.666666666667
CDK5 CDK5R1
Activated NTRK2 signals through CDK5
KEGG:05030
0.000624850267462
0.666666666667
CDK5 CDK5R1
Cocaine addiction
REAC:R-HSA-399956
0.000715513386354
0.666666666667
CDK5 CDK5R1
CRMPs in Sema3A signaling
WP:WP3878
0.000927197171072
0.666666666667
CDK5 CDK5R1
ATM signaling in development and disease
REAC:R-HSA-9768919
0.00104246243986
0.666666666667
CDK5 CDK5R1
NPAS4 regulates expression of target genes
REAC:R-HSA-9006115
0.00104246243986
0.666666666667
CDK5 CDK5R1
Signaling by NTRK2 (TRKB)
GO:0016533
0.00140460216025
0.666666666667
CDK5 CDK5R1
protein kinase 5 complex
REAC:R-HSA-8863678
0.00143063482691
0.666666666667
CDK5 CDK5R1
Neurodegenerative Diseases
REAC:R-HSA-8862803
0.00143063482691
0.666666666667
CDK5 CDK5R1
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
REAC:R-HSA-9734009
0.00188000535098
0.666666666667
CDK5 CDK5R1
Defective Intrinsic Pathway for Apoptosis
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Edges
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Protein 1
Protein 2
Score
?
ProteomeHD
?
Evidence
?
CDK5
CDK5R1
0.999
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
CDK5
CCNI
0.993
bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only
Showing 1 to 2 of 2 entries
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Related Complexes
Genename
Complexes
CDK5
huMAP3_04028.1
huMAP3_04468.1
huMAP3_06311.1
huMAP3_06587.1
huMAP3_09793.1
huMAP3_10253.1
huMAP3_10449.1
huMAP3_11987.1
huMAP3_14722.1
huMAP3_15344.1
CDK5R1
huMAP3_04028.1
huMAP3_04468.1
huMAP3_06587.1
huMAP3_08377.1
huMAP3_09319.1
huMAP3_09793.1
huMAP3_10253.1
huMAP3_10449.1
huMAP3_15344.1
CCNI
huMAP3_04028.1
huMAP3_04468.1
huMAP3_06311.1
huMAP3_09793.1
huMAP3_10253.1
huMAP3_10449.1
huMAP3_11987.1
huMAP3_14722.1
huMAP3_15344.1