hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_04031.1
Complex Portal: CPX-11677
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SIM1 | Single-minded homolog 1 (Class E basic helix-loop-helix protein 14) (bHLHe14) | 4 | UniProt NCBI |
| ARNT2 | Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2) (Class E basic helix-loop-helix protein 1) (bHLHe1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0011787 | 0.00604901660254 | 1.0 | SIM1 ARNT2 | Central hypothyroidism |
| HP:0005307 | 0.0499436884913 | 0.5 | SIM1 | Postural hypotension with compensatory tachycardia |
| HP:0012339 | 0.0499436884913 | 0.5 | SIM1 | Increased resting energy expenditure |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| SIM1 | ARNT2 | 0.994 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes
| Genename | Complexes |
|---|---|
| SIM1 | huMAP3_04031.1 huMAP3_13171.1 huMAP3_14050.1 |
| ARNT2 | huMAP3_04031.1 huMAP3_13171.1 huMAP3_14050.1 |