hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_04042.1
Complex Portal: CPX-18303
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GRAMD2A | GRAM domain-containing protein 2A | 5 | UniProt NCBI |
| GRAMD1B | Protein Aster-B (GRAM domain-containing protein 1B) | 5 | UniProt NCBI |
| GRAMD2B | GRAM domain-containing protein 2B (HCV NS3-transactivated protein 2) | 5 | UniProt NCBI |
| GRAMD1A | Protein Aster-A (GRAM domain-containing protein 1A) | 5 | UniProt NCBI |
| GRAMD1C | Protein Aster-C (GRAM domain-containing protein 1C) | 4 | UniProt NCBI |
| EFCAB14 | EF-hand calcium-binding domain-containing protein 14 | 2 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0044232 | 5.85430293603e-05 | 0.666666666667 | GRAMD2A GRAMD1C GRAMD1B GRAMD1A | organelle membrane contact site |
| GO:0071397 | 0.0002304395259 | 0.5 | GRAMD1C GRAMD1B GRAMD1A | cellular response to cholesterol |
| GO:0140268 | 0.000316805542726 | 0.5 | GRAMD1C GRAMD1B GRAMD1A | endoplasmic reticulum-plasma membrane contact site |
| GO:0120020 | 0.000548960443183 | 0.5 | GRAMD1C GRAMD1B GRAMD1A | cholesterol transfer activity |
| GO:0036315 | 0.000548960443183 | 0.5 | GRAMD1C GRAMD1B GRAMD1A | cellular response to sterol |
| GO:0120015 | 0.000698569295426 | 0.5 | GRAMD1C GRAMD1B GRAMD1A | sterol transfer activity |
| GO:0070723 | 0.0010743908712 | 0.5 | GRAMD1C GRAMD1B GRAMD1A | response to cholesterol |
| GO:0036314 | 0.00185822071527 | 0.5 | GRAMD1C GRAMD1B GRAMD1A | response to sterol |
| GO:0032366 | 0.00295184433846 | 0.5 | GRAMD1C GRAMD1B GRAMD1A | intracellular sterol transport |
| GO:0015248 | 0.00498056162807 | 0.5 | GRAMD1C GRAMD1B GRAMD1A | sterol transporter activity |
| GO:0032365 | 0.0125202207278 | 0.5 | GRAMD1C GRAMD1B GRAMD1A | intracellular lipid transport |
| GO:0015485 | 0.0161301339283 | 0.5 | GRAMD1C GRAMD1B GRAMD1A | cholesterol binding |
| GO:0120013 | 0.017471616814 | 0.5 | GRAMD1C GRAMD1B GRAMD1A | lipid transfer activity |
| GO:0097306 | 0.0203731249082 | 0.5 | GRAMD1C GRAMD1B GRAMD1A | cellular response to alcohol |
| GO:0032934 | 0.0309610298034 | 0.5 | GRAMD1C GRAMD1B GRAMD1A | sterol binding |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| GRAMD1A | GRAMD1B | 1.0 | 0.146 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 | |
| GRAMD1C | GRAMD1B | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| GRAMD2B | GRAMD1C | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| GRAMD2B | GRAMD1B | 0.999 | 0.098 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 | |
| GRAMD2B | GRAMD1A | 0.999 | 0.148 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 | |
| EFCAB14 | GRAMD2B | 0.998 | 0.1 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| GRAMD1C | GRAMD1A | 0.978 | bioplex_WMM bioplex3_WMM WMM_only | ||
| GRAMD2A | GRAMD2B | 0.977 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| GRAMD2A | GRAMD1B | 0.976 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| EFCAB14 | GRAMD1C | 0.936 | bioplex_WMM bioplex3_WMM WMM_only | ||
| EFCAB14 | GRAMD1B | 0.936 | 0.136 | bioplex_WMM bioplex3_WMM WMM_only | |
| EFCAB14 | GRAMD2A | 0.902 | bioplex3_WMM WMM_only | ||
| EFCAB14 | GRAMD1A | 0.839 | 0.112 | bioplex_WMM bioplex3_WMM WMM_only | |
| GRAMD2A | GRAMD1C | 0.596 | bioplex3_WMM WMM_only | ||
| GRAMD2A | GRAMD1A | 0.586 | bioplex3_WMM WMM_only |
Related Complexes