hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_04048.1
Complex Portal: CPX-14706
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PEX16 | Peroxisomal membrane protein PEX16 (Peroxin-16) (Peroxisomal biogenesis factor 16) | 5 | UniProt NCBI |
| HSD11B2 | 11-beta-hydroxysteroid dehydrogenase type 2 (11-DH2) (11-beta-HSD2) (EC 1.1.1.-) (11-beta-hydroxysteroid dehydrogenase type II) (11-HSD type II) (11-beta-HSD type II) (Corticosteroid 11-beta-dehydrogenase isozyme 2) (NAD-dependent 11-beta-hydroxysteroid dehydrogenase) (Short chain dehydrogenase/reductase family 9C member 3) | 5 | UniProt NCBI |
| DTWD1 | tRNA-uridine aminocarboxypropyltransferase 1 (EC 2.5.1.25) (DTW domain-containing protein 1) | 4 | UniProt NCBI |
| GPR182 | G-protein coupled receptor 182 | 4 | UniProt NCBI |
| LIPE | Hormone-sensitive lipase (HSL) (EC 3.1.1.79) (Monoacylglycerol lipase LIPE) (EC 3.1.1.23) (Retinyl ester hydrolase) (REH) | 5 | UniProt NCBI |
| PLPP6 | Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6 (EC 3.1.3.-) (EC 3.6.1.-) (EC 3.6.1.68) (Lipid phosphatase-related protein-B) (LPRP-B) (PA-PSP) (Phosphatidic acid phosphatase type 2 domain-containing protein 2) (PPAP2 domain-containing protein 2) (Phospholipid phosphatase 6) (Presqualene diphosphate phosphatase) (Type 1 polyisoprenoid diphosphate phosphatase) | 5 | UniProt NCBI |
| COQ6 | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial (EC 1.14.13.-) (Coenzyme Q10 monooxygenase 6) | 5 | UniProt NCBI |
| UBE3B | Ubiquitin-protein ligase E3B (EC 2.3.2.26) (HECT-type ubiquitin transferase E3B) | 4 | UniProt NCBI |
| CLMN | Calmin (Calponin-like transmembrane domain protein) | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0000055 | 0.0471022227504 | 0.333333333333 | PEX16 LIPE UBE3B | Abnormal female external genitalia morphology |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| CLMN | GPR182 | 0.998 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| DTWD1 | GPR182 | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| HSD11B2 | GPR182 | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| UBE3B | GPR182 | 0.997 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| LIPE | GPR182 | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| GPR182 | COQ6 | 0.996 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| PEX16 | GPR182 | 0.996 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| PLPP6 | GPR182 | 0.984 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| CLMN | HSD11B2 | 0.904 | 0.064 | bioplex3_WMM WMM_only | |
| UBE3B | HSD11B2 | 0.904 | 0.052 | bioplex3_WMM WMM_only | |
| LIPE | HSD11B2 | 0.902 | 0.146 | bioplex3_WMM WMM_only | |
| DTWD1 | HSD11B2 | 0.902 | 0.05 | bioplex3_WMM WMM_only | |
| PEX16 | HSD11B2 | 0.73 | 0.07 | bioplex3_WMM WMM_only | |
| LIPE | DTWD1 | 0.714 | 0.05 | bioplex3_WMM WMM_only | |
| LIPE | PEX16 | 0.675 | 0.024 | bioplex3_WMM WMM_only | |
| PLPP6 | HSD11B2 | 0.651 | 0.048 | bioplex3_WMM WMM_only | |
| PEX16 | DTWD1 | 0.631 | 0.05 | bioplex3_WMM WMM_only | |
| HSD11B2 | COQ6 | 0.626 | 0.074 | bioplex3_WMM WMM_only | |
| LIPE | PLPP6 | 0.606 | 0.04 | bioplex3_WMM WMM_only | |
| PEX16 | CLMN | 0.552 | 0.024 | bioplex3_WMM WMM_only | |
| UBE3B | PEX16 | 0.552 | 0.09 | bioplex3_WMM WMM_only | |
| LIPE | CLMN | 0.478 | 0.07 | bioplex3_WMM WMM_only | |
| UBE3B | LIPE | 0.455 | 0.124 | bioplex3_WMM WMM_only | |
| CLMN | PLPP6 | 0.439 | 0.052 | bioplex3_WMM youn_WMM WMM_only | |
| PEX16 | PLPP6 | 0.438 | 0.068 | bioplex_WMM bioplex3_WMM WMM_only | |
| LIPE | COQ6 | 0.418 | 0.016 | bioplex3_WMM WMM_only | |
| UBE3B | CLMN | 0.356 | 0.066 | bioplex3_WMM WMM_only | |
| DTWD1 | CLMN | 0.356 | 0.042 | bioplex3_WMM WMM_only | |
| UBE3B | DTWD1 | 0.334 | 0.134 | bioplex3_WMM WMM_only | |
| DTWD1 | PLPP6 | 0.271 | 0.08 | bioplex3_WMM WMM_only | |
| PLPP6 | COQ6 | 0.26 | 0.068 | bioplex_WMM bioplex3_WMM WMM_only | |
| UBE3B | PLPP6 | 0.26 | 0.066 | bioplex3_WMM WMM_only | |
| PEX16 | COQ6 | 0.251 | 0.028 | bioplex3_WMM WMM_only | |
| CLMN | COQ6 | 0.205 | 0.076 | bioplex3_WMM WMM_only | |
| DTWD1 | COQ6 | 0.188 | 0.062 | bioplex3_WMM WMM_only | |
| UBE3B | COQ6 | 0.169 | 0.044 | bioplex3_WMM WMM_only |
Related Complexes