hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_04055.1
Complex Portal: CPX-10660
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| AGPAT4 | 1-acyl-sn-glycerol-3-phosphate acyltransferase delta (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 4) (1-AGP acyltransferase 4) (1-AGPAT 4) (Lysophosphatidic acid acyltransferase delta) (LPAAT-delta) | 5 | UniProt NCBI |
| SC5D | Lathosterol oxidase (EC 1.14.19.20) (C-5 sterol desaturase) (Delta(7)-sterol 5-desaturase) (Delta(7)-sterol C5(6)-desaturase) (Lathosterol 5-desaturase) (Sterol-C5-desaturase) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00100 | 0.0379931878772 | 0.5 | SC5D | Steroid biosynthesis |
| WP:WP4804 | 0.0435328773163 | 0.5 | SC5D | Cholesterol biosynthesis with skeletal dysplasias |
| HP:0034936 | 0.0499436884913 | 0.5 | SC5D | Elevated circulating lathosterol concentration |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| AGPAT4 | SC5D | 0.951 | 0.102 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| AGPAT4 | huMAP3_04055.1 huMAP3_07868.1 huMAP3_09605.1 huMAP3_09975.1 |
| SC5D | huMAP3_04055.1 huMAP3_07868.1 huMAP3_09605.1 huMAP3_09975.1 huMAP3_12126.1 |