hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_04068.1
Complex Portal: CPX-13263
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| IRF3 | Interferon regulatory factor 3 (IRF-3) | 5 | UniProt NCBI |
| AHSA1 | Activator of 90 kDa heat shock protein ATPase homolog 1 (AHA1) (p38) | 5 | UniProt NCBI |
| USP19 | Ubiquitin carboxyl-terminal hydrolase 19 (EC 3.4.19.12) (Deubiquitinating enzyme 19) (Ubiquitin thioesterase 19) (Ubiquitin-specific-processing protease 19) (Zinc finger MYND domain-containing protein 9) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP5187 | 0.0496447587094 | 0.333333333333 | IRF3 | mRNA vaccine activation of dendritic cell and induction of IFN 1 |
| CORUM:299 | 0.0499402709677 | 0.333333333333 | IRF3 | IRF3-CBP complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| IRF3 | AHSA1 | 0.976 | 0.158 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| USP19 | IRF3 | 0.975 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| USP19 | AHSA1 | 0.016 | bioplex_WMM bioplex3_WMM gupta_WMM fraction |
Related Complexes