hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_04073.1
Complex Portal: CPX-12758
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MAGOHB | Protein mago nashi homolog 2 | 5 | UniProt NCBI |
| MAGOH | Protein mago nashi homolog | 5 | UniProt NCBI |
| PYM1 | Partner of Y14 and mago (PYM homolog 1 exon junction complex-associated factor) (Protein wibg homolog) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:03015 | 6.34627347292e-06 | 1.0 | MAGOH MAGOHB PYM1 | mRNA surveillance pathway |
| KEGG:03013 | 8.70565480728e-06 | 1.0 | MAGOH MAGOHB PYM1 | Nucleocytoplasmic transport |
| CORUM:755 | 3.41705576683e-05 | 0.666666666667 | MAGOH PYM1 | Exon junction complex (EIF4A3, MLN51, UPF3B, MAGOH, Y14, PYM) |
| GO:0035145 | 0.000109576846827 | 1.0 | MAGOH MAGOHB PYM1 | exon-exon junction complex |
| GO:0000184 | 0.000524430944113 | 1.0 | MAGOH MAGOHB PYM1 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
| WP:WP5362 | 0.00132925024934 | 0.666666666667 | MAGOH PYM1 | TAR syndrome |
| GO:1990501 | 0.00421361424067 | 0.666666666667 | MAGOH MAGOHB | exon-exon junction subcomplex mago-y14 |
| GO:1903503 | 0.00421361424067 | 0.666666666667 | MAGOH MAGOHB | ATPase inhibitor complex |
| KEGG:03040 | 0.00588292524774 | 0.666666666667 | MAGOH MAGOHB | Spliceosome |
| REAC:R-HSA-72187 | 0.0101009261622 | 0.666666666667 | MAGOH MAGOHB | mRNA 3'-end processing |
| REAC:R-HSA-73856 | 0.0132793882188 | 0.666666666667 | MAGOH MAGOHB | RNA Polymerase II Transcription Termination |
| REAC:R-HSA-159236 | 0.0164154902665 | 0.666666666667 | MAGOH MAGOHB | Transport of Mature mRNA derived from an Intron-Containing Transcript |
| REAC:R-HSA-72202 | 0.0209338694285 | 0.666666666667 | MAGOH MAGOHB | Transport of Mature Transcript to Cytoplasm |
| GO:0000956 | 0.0219076797621 | 1.0 | MAGOH MAGOHB PYM1 | nuclear-transcribed mRNA catabolic process |
| REAC:R-HSA-927802 | 0.0436932800731 | 0.666666666667 | MAGOH MAGOHB | Nonsense-Mediated Decay (NMD) |
| REAC:R-HSA-975957 | 0.0436932800731 | 0.666666666667 | MAGOH MAGOHB | Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) |
| CORUM:773 | 0.0499402709677 | 0.333333333333 | MAGOH | Y14-Magoh complex |
| CORUM:763 | 0.0499402709677 | 0.333333333333 | MAGOH | Y14-Magoh complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| MAGOH | PYM1 | 0.997 |
structurally_consistent (dimer)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 | |
| MAGOH | MAGOHB | 0.994 | hein_WMM bioplex3_WMM hein () gupta_WMM | ||
| PYM1 | MAGOHB | 0.854 | 0.1 |
mutually_exclusive (P38919)
structurally_consistent (dimer) |
hein_WMM bioplex3_WMM hein () |
Related Complexes