hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_04077.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ZNF668 | Zinc finger protein 668 | 5 | UniProt NCBI |
| TAF1C | TATA box-binding protein-associated factor RNA polymerase I subunit C (RNA polymerase I-specific TBP-associated factor 110 kDa) (TAFI110) (TATA box-binding protein-associated factor 1C) (TBP-associated factor 1C) (Transcription initiation factor SL1/TIF-IB subunit C) | 5 | UniProt NCBI |
| TAF1A | TATA box-binding protein-associated factor RNA polymerase I subunit A (RNA polymerase I-specific TBP-associated factor 48 kDa) (TAFI48) (TATA box-binding protein-associated factor 1A) (TBP-associated factor 1A) (Transcription factor SL1) (Transcription initiation factor SL1/TIF-IB subunit A) | 5 | UniProt NCBI |
| DDX52 | Probable ATP-dependent RNA helicase DDX52 (EC 3.6.4.13) (ATP-dependent RNA helicase ROK1-like) (DEAD box protein 52) | 5 | UniProt NCBI |
| NSD2 | Histone-lysine N-methyltransferase NSD2 (EC 2.1.1.357) (Multiple myeloma SET domain-containing protein) (MMSET) (Nuclear SET domain-containing protein 2) (Protein trithorax-5) (Wolf-Hirschhorn syndrome candidate 1 protein) | 5 | UniProt NCBI |
| RBMX2 | RNA-binding motif protein, X-linked 2 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:5727 | 0.000102488289015 | 0.333333333333 | TAF1C TAF1A | TBP-TAF complex |
| REAC:R-HSA-73863 | 0.0119428487471 | 0.333333333333 | TAF1C TAF1A | RNA Polymerase I Transcription Termination |
| REAC:R-HSA-73762 | 0.0276828753036 | 0.333333333333 | TAF1C TAF1A | RNA Polymerase I Transcription Initiation |
| REAC:R-HSA-427359 | 0.0393724000146 | 0.333333333333 | TAF1C TAF1A | SIRT1 negatively regulates rRNA expression |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| TAF1A | TAF1C | 0.998 | 0.178 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 treiber_WMM |
| TAF1A | ZNF668 | 0.993 | 0.128 | hein_WMM bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| ZNF668 | RBMX2 | 0.99 | 0.146 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| ZNF668 | NSD2 | 0.986 | 0.144 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| DDX52 | ZNF668 | 0.975 | 0.22 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| TAF1C | ZNF668 | 0.961 | 0.134 | bioplex_WMM bioplex3_WMM WMM_only |
| NSD2 | RBMX2 | 0.931 | 0.138 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| TAF1A | RBMX2 | 0.877 | 0.176 | bioplex_WMM bioplex3_WMM WMM_only treiber_WMM |
| TAF1A | NSD2 | 0.824 | 0.162 | bioplex_WMM bioplex3_WMM WMM_only |
| DDX52 | NSD2 | 0.822 | 0.088 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| DDX52 | RBMX2 | 0.811 | 0.234 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only treiber_WMM |
| TAF1C | NSD2 | 0.725 | 0.19 | bioplex_WMM bioplex3_WMM WMM_only |
| TAF1C | RBMX2 | 0.651 | 0.124 | bioplex_WMM bioplex3_WMM WMM_only |
| TAF1A | DDX52 | 0.454 | 0.104 | bioplex_WMM bioplex3_WMM WMM_only treiber_WMM |
| TAF1C | DDX52 | 0.327 | 0.062 | bioplex_WMM bioplex3_WMM WMM_only treiber_WMM |
Related Complexes