hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_04091.1
Complex Portal: CPX-16259
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MMACHC | Cyanocobalamin reductase / alkylcobalamin dealkylase (Alkylcobalamin:glutathione S-alkyltransferase) (EC 2.5.1.151) (CblC) (Cyanocobalamin reductase (cyanide-eliminating)) (EC 1.16.1.6) (Methylmalonic aciduria and homocystinuria type C protein) (MMACHC) | 5 | UniProt NCBI |
| TBC1D17 | TBC1 domain family member 17 | 5 | UniProt NCBI |
| BNIP5 | Protein BNIP5 | 2 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-3359474 | 0.0498224659464 | 0.333333333333 | MMACHC | Defective MMACHC causes MAHCC |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| BNIP5 | TBC1D17 | 0.966 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| MMACHC | BNIP5 | 0.96 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| MMACHC | TBC1D17 | 0.076 | 0.07 | bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| MMACHC | huMAP3_00592.1 huMAP3_04091.1 huMAP3_11460.1 |
| TBC1D17 | huMAP3_04091.1 huMAP3_09413.1 huMAP3_10751.1 huMAP3_11337.1 huMAP3_11460.1 huMAP3_13492.1 |
| BNIP5 | huMAP3_00592.1 huMAP3_04091.1 huMAP3_11337.1 huMAP3_11460.1 huMAP3_13492.1 |