hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_04101.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SYNJ1 | Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1) | 5 | UniProt NCBI |
| REPS1 | RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1) | 5 | UniProt NCBI |
| REPS2 | RalBP1-associated Eps domain-containing protein 2 (Partner of RalBP1) (RalBP1-interacting protein 2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-8856828 | 0.00018294723391 | 1.0 | SYNJ1 REPS2 REPS1 | Clathrin-mediated endocytosis |
| WP:WP437 | 0.0115871748317 | 0.666666666667 | SYNJ1 REPS2 | EGF EGFR signaling pathway |
| REAC:R-HSA-199991 | 0.0145539954891 | 1.0 | SYNJ1 REPS2 REPS1 | Membrane Trafficking |
| REAC:R-HSA-5653656 | 0.017135828319 | 1.0 | SYNJ1 REPS2 REPS1 | Vesicle-mediated transport |
| REAC:R-HSA-8856825 | 0.0296783854994 | 0.666666666667 | REPS1 REPS2 | Cargo recognition for clathrin-mediated endocytosis |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| REPS2 | REPS1 | 0.998 | 0.144 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 |
| SYNJ1 | REPS1 | 0.953 | 0.188 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| SYNJ1 | REPS2 | 0.066 | 0.052 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
Related Complexes