hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_04104.1
Complex Portal: CPX-25697
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ELP4 | Elongator complex protein 4 (hELP4) (PAX6 neighbor gene protein) | 5 | UniProt NCBI |
| ELP5 | Elongator complex protein 5 (Dermal papilla-derived protein 6) (S-phase 2 protein) | 5 | UniProt NCBI |
| ELP6 | Elongator complex protein 6 (Angiotonin-transactivated protein 1) (Protein TMEM103) | 5 | UniProt NCBI |
| LALBA | Alpha-lactalbumin (Lactose synthase B protein) (Lysozyme-like protein 7) | 5 | UniProt NCBI |
| PIPOX | Peroxisomal sarcosine oxidase (PSO) (EC 1.5.3.1) (EC 1.5.3.7) (L-pipecolate oxidase) (L-pipecolic acid oxidase) | 5 | UniProt NCBI |
| CSN3 | Kappa-casein | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6332 | 9.35042757897e-08 | 0.5 | ELP4 ELP5 ELP6 | Elongator complex (ELP1, ELP2, ELP3, ELP4, ELP5, ELP6) |
| GO:0033588 | 3.84302573496e-05 | 0.5 | ELP4 ELP5 ELP6 | elongator holoenzyme complex |
| HPA:0280383 | 0.000208040086454 | 0.333333333333 | CSN3 LALBA | lactating breast; lactating glandular cells[High] |
| HPA:0280382 | 0.000388199755762 | 0.333333333333 | CSN3 LALBA | lactating breast; lactating glandular cells[>=Medium] |
| HPA:0280000 | 0.000499022874847 | 0.333333333333 | CSN3 LALBA | lactating breast |
| HPA:0280381 | 0.000499022874847 | 0.333333333333 | CSN3 LALBA | lactating breast; lactating glandular cells[>=Low] |
| GO:0002098 | 0.00130441648129 | 0.5 | ELP4 ELP5 ELP6 | tRNA wobble uridine modification |
| GO:0002097 | 0.00218580514948 | 0.5 | ELP4 ELP5 ELP6 | tRNA wobble base modification |
| REAC:R-HSA-3214847 | 0.00242257327817 | 0.5 | ELP4 ELP5 ELP6 | HATs acetylate histones |
| REAC:R-HSA-3247509 | 0.0175026890485 | 0.5 | ELP4 ELP5 ELP6 | Chromatin modifying enzymes |
| REAC:R-HSA-4839726 | 0.0175026890485 | 0.5 | ELP4 ELP5 ELP6 | Chromatin organization |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ELP5 | ELP6 | 1.0 | 0.386 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM | |
| ELP4 | ELP6 | 1.0 | 0.57 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM | |
| PIPOX | ELP5 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| LALBA | PIPOX | 0.998 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| PIPOX | ELP6 | 0.997 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| PIPOX | CSN3 | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| ELP4 | ELP5 | 0.996 | 0.438 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM WMM_only | |
| PIPOX | ELP4 | 0.986 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| LALBA | CSN3 | 0.902 | bioplex3_WMM WMM_only | ||
| LALBA | ELP5 | 0.902 | bioplex3_WMM WMM_only | ||
| LALBA | ELP6 | 0.869 | bioplex3_WMM WMM_only | ||
| CSN3 | ELP6 | 0.227 | bioplex3_WMM youn_WMM gupta_WMM WMM_only | ||
| CSN3 | ELP5 | 0.219 | bioplex3_WMM youn_WMM gupta_WMM WMM_only | ||
| LALBA | ELP4 | 0.214 | bioplex3_WMM WMM_only | ||
| CSN3 | ELP4 | 0.015 | bioplex3_WMM youn_WMM gupta_WMM WMM_only |
Related Complexes