hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_04115.1
Complex Portal: CPX-18876
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| NOA1 | Nitric oxide-associated protein 1 | 5 | UniProt NCBI |
| MRPS18C | Small ribosomal subunit protein bS18m (28S ribosomal protein S18-1, mitochondrial) (MRP-S18-1) (28S ribosomal protein S18c, mitochondrial) (MRP-S18-c) (Mrps18-c) (S18mt-c) (Small ribosomal subunit protein bS18c) | 3 | UniProt NCBI |
| MRPS34 | Small ribosomal subunit protein mS34 (28S ribosomal protein S34, mitochondrial) (MRP-S34) (S34mt) | 5 | UniProt NCBI |
| MRPS12 | Small ribosomal subunit protein uS12m (28S ribosomal protein S12, mitochondrial) (MRP-S12) (S12mt) (MT-RPS12) | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:315 | 2.84457331044e-06 | 0.75 | MRPS12 MRPS18C MRPS34 | 28S ribosomal subunit, mitochondrial |
| CORUM:320 | 5.31699160505e-05 | 0.75 | MRPS12 MRPS18C MRPS34 | 55S ribosome, mitochondrial |
| REAC:R-HSA-5389840 | 0.000148092217351 | 0.75 | MRPS12 MRPS18C MRPS34 | Mitochondrial translation elongation |
| REAC:R-HSA-5368286 | 0.000148092217351 | 0.75 | MRPS12 MRPS18C MRPS34 | Mitochondrial translation initiation |
| REAC:R-HSA-5419276 | 0.000148092217351 | 0.75 | MRPS12 MRPS18C MRPS34 | Mitochondrial translation termination |
| REAC:R-HSA-5368287 | 0.000181248084935 | 0.75 | MRPS12 MRPS18C MRPS34 | Mitochondrial translation |
| GO:0000314 | 0.00190418300832 | 0.75 | MRPS12 MRPS18C MRPS34 | organellar small ribosomal subunit |
| GO:0005763 | 0.00190418300832 | 0.75 | MRPS12 MRPS18C MRPS34 | mitochondrial small ribosomal subunit |
| REAC:R-HSA-72766 | 0.00544769255683 | 0.75 | MRPS12 MRPS18C MRPS34 | Translation |
| KEGG:03010 | 0.0207865818092 | 0.5 | MRPS18C MRPS12 | Ribosome |
| GO:0005743 | 0.0257556797055 | 1.0 | MRPS12 MRPS34 NOA1 MRPS18C | mitochondrial inner membrane |
| GO:0015935 | 0.0258660780327 | 0.75 | MRPS12 MRPS18C MRPS34 | small ribosomal subunit |
| GO:0019866 | 0.0323627079397 | 1.0 | MRPS12 MRPS34 NOA1 MRPS18C | organelle inner membrane |
| GO:0000313 | 0.0420072408269 | 0.75 | MRPS12 MRPS18C MRPS34 | organellar ribosome |
| GO:0005761 | 0.0420072408269 | 0.75 | MRPS12 MRPS18C MRPS34 | mitochondrial ribosome |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| MRPS18C | MRPS34 | 0.997 | 0.768 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 fraction boldt_WMM treiber_WMM | |
| MRPS34 | NOA1 | 0.993 | 0.224 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| MRPS34 | MRPS12 | 0.99 | 0.866 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 treiber_WMM | |
| MRPS18C | MRPS12 | 0.978 | 0.306 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| MRPS18C | NOA1 | 0.974 | 0.12 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| NOA1 | MRPS12 | 0.964 | 0.116 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| NOA1 | huMAP3_02367.1 huMAP3_04115.1 huMAP3_05807.1 huMAP3_05954.1 huMAP3_06043.1 |
| MRPS18C | huMAP3_01034.1 huMAP3_04115.1 huMAP3_05807.1 huMAP3_05954.1 |
| MRPS34 | huMAP3_01034.1 huMAP3_04115.1 huMAP3_05807.1 huMAP3_05954.1 |
| MRPS12 | huMAP3_02367.1 huMAP3_04115.1 huMAP3_05807.1 huMAP3_05954.1 huMAP3_06043.1 |