hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_04133.1
Complex Portal: CPX-21079
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ST6GALNAC5 | Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 (EC 2.4.99.-) (GD1 alpha synthase) (GalNAc alpha-2,6-sialyltransferase V) (ST6GalNAc V) (ST6GalNAcV) (Sialyltransferase 7E) (SIAT7-E) | 5 | UniProt NCBI |
| FBP1 | Fructose-1,6-bisphosphatase 1 (FBPase 1) (EC 3.1.3.11) (D-fructose-1,6-bisphosphate 1-phosphohydrolase 1) (Liver FBPase) | 5 | UniProt NCBI |
| ILDR1 | Immunoglobulin-like domain-containing receptor 1 (Angulin-2) | 5 | UniProt NCBI |
| FBP2 | Fructose-1,6-bisphosphatase isozyme 2 (FBPase 2) (EC 3.1.3.11) (D-fructose-1,6-bisphosphate 1-phosphohydrolase 2) (Muscle FBPase) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0009312 | 0.000510886175237 | 0.75 | ST6GALNAC5 FBP1 FBP2 | oligosaccharide biosynthetic process |
| KEGG:00030 | 0.000878377582941 | 0.5 | FBP2 FBP1 | Pentose phosphate pathway |
| KEGG:00051 | 0.0014030052018 | 0.5 | FBP2 FBP1 | Fructose and mannose metabolism |
| WP:WP534 | 0.002190823719 | 0.5 | FBP2 FBP1 | Glycolysis and gluconeogenesis |
| GO:0042132 | 0.0028092043205 | 0.5 | FBP2 FBP1 | fructose 1,6-bisphosphate 1-phosphatase activity |
| GO:0005986 | 0.0028092043205 | 0.5 | FBP2 FBP1 | sucrose biosynthetic process |
| REAC:R-HSA-70263 | 0.00359044851421 | 0.5 | FBP2 FBP1 | Gluconeogenesis |
| KEGG:00010 | 0.00471711368352 | 0.5 | FBP2 FBP1 | Glycolysis / Gluconeogenesis |
| GO:0009311 | 0.00473512798232 | 0.75 | ST6GALNAC5 FBP1 FBP2 | oligosaccharide metabolic process |
| GO:0005985 | 0.00842684400117 | 0.5 | FBP2 FBP1 | sucrose metabolic process |
| WP:WP5355 | 0.0092628309276 | 0.5 | FBP2 FBP1 | Metabolic Epileptic Disorders |
| KEGG:04922 | 0.0104133784038 | 0.5 | FBP2 FBP1 | Glucagon signaling pathway |
| KEGG:01200 | 0.0133093129958 | 0.5 | FBP2 FBP1 | Carbon metabolism |
| KEGG:04152 | 0.0157117070582 | 0.5 | FBP2 FBP1 | AMPK signaling pathway |
| GO:0046351 | 0.0168521501606 | 0.5 | FBP2 FBP1 | disaccharide biosynthetic process |
| KEGG:04910 | 0.0195294442288 | 0.5 | FBP2 FBP1 | Insulin signaling pathway |
| REAC:R-HSA-70326 | 0.0313666733646 | 0.5 | FBP2 FBP1 | Glucose metabolism |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| FBP1 | FBP2 | 1.0 | 0.216 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| FBP1 | ILDR1 | 0.99 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| ST6GALNAC5 | FBP1 | 0.969 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
Related Complexes
| Genename | Complexes |
|---|---|
| ST6GALNAC5 | huMAP3_04133.1 huMAP3_08433.1 huMAP3_12551.1 |
| FBP1 | huMAP3_04133.1 huMAP3_12551.1 |
| ILDR1 | huMAP3_04133.1 huMAP3_04262.1 huMAP3_06102.1 huMAP3_06903.1 huMAP3_07815.1 huMAP3_08343.1 huMAP3_09367.1 huMAP3_10060.1 huMAP3_11781.1 |
| FBP2 | huMAP3_04133.1 huMAP3_12551.1 |