hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_04135.1
Complex Portal: CPX-16989
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MRPS28 | Small ribosomal subunit protein bS1m (28S ribosomal protein S28, mitochondrial) (MRP-S28) (S28mt) (28S ribosomal protein S35, mitochondrial) (MRP-S35) (S35mt) | 4 | UniProt NCBI |
| DNAJC21 | DnaJ homolog subfamily C member 21 (DnaJ homolog subfamily A member 5) (Protein GS3) | 5 | UniProt NCBI |
| MRPS16 | Small ribosomal subunit protein bS16m (28S ribosomal protein S16, mitochondrial) (MRP-S16) (S16mt) | 5 | UniProt NCBI |
| MRPS18B | Small ribosomal subunit protein mS40 (28S ribosomal protein S18-2, mitochondrial) (MRP-S18-2) (28S ribosomal protein S18b, mitochondrial) (MRP-S18-b) (Mrps18-b) (S18mt-b) (Small ribosomal subunit protein bS18b) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:315 | 2.84457331044e-06 | 0.75 | MRPS18B MRPS28 MRPS16 | 28S ribosomal subunit, mitochondrial |
| CORUM:320 | 5.31699160505e-05 | 0.75 | MRPS18B MRPS28 MRPS16 | 55S ribosome, mitochondrial |
| REAC:R-HSA-5419276 | 0.000148092217351 | 0.75 | MRPS18B MRPS28 MRPS16 | Mitochondrial translation termination |
| REAC:R-HSA-5389840 | 0.000148092217351 | 0.75 | MRPS18B MRPS28 MRPS16 | Mitochondrial translation elongation |
| REAC:R-HSA-5368286 | 0.000148092217351 | 0.75 | MRPS18B MRPS28 MRPS16 | Mitochondrial translation initiation |
| REAC:R-HSA-5368287 | 0.000181248084935 | 0.75 | MRPS18B MRPS28 MRPS16 | Mitochondrial translation |
| GO:0000314 | 0.00190418300832 | 0.75 | MRPS18B MRPS28 MRPS16 | organellar small ribosomal subunit |
| GO:0005763 | 0.00190418300832 | 0.75 | MRPS18B MRPS28 MRPS16 | mitochondrial small ribosomal subunit |
| GO:0005840 | 0.00207182130674 | 1.0 | MRPS16 MRPS18B MRPS28 DNAJC21 | ribosome |
| REAC:R-HSA-72766 | 0.00544769255683 | 0.75 | MRPS18B MRPS28 MRPS16 | Translation |
| HPA:0430053 | 0.00577234238213 | 1.0 | MRPS16 MRPS18B MRPS28 DNAJC21 | seminal vesicle; glandular cells[High] |
| HP:0002910 | 0.0232389637101 | 0.75 | MRPS16 MRPS28 DNAJC21 | Elevated hepatic transaminase |
| GO:0015935 | 0.0258660780327 | 0.75 | MRPS18B MRPS28 MRPS16 | small ribosomal subunit |
| HPA:0570812 | 0.0387789758455 | 1.0 | MRPS16 MRPS18B MRPS28 DNAJC21 | testis; spermatogonia cells[>=Medium] |
| HPA:0550053 | 0.0399271079825 | 1.0 | MRPS16 MRPS18B MRPS28 DNAJC21 | stomach 2; glandular cells[High] |
| HPA:0540053 | 0.0408047952341 | 1.0 | MRPS16 MRPS18B MRPS28 DNAJC21 | stomach 1; glandular cells[High] |
| GO:0005761 | 0.0420072408269 | 0.75 | MRPS18B MRPS28 MRPS16 | mitochondrial ribosome |
| GO:0000313 | 0.0420072408269 | 0.75 | MRPS18B MRPS28 MRPS16 | organellar ribosome |
| HPA:0480053 | 0.048862114603 | 1.0 | MRPS16 MRPS18B MRPS28 DNAJC21 | small intestine; glandular cells[High] |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| MRPS28 | MRPS18B | 0.998 | 0.888 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM treiber_WMM WMM_only | |
| MRPS16 | MRPS18B | 0.997 | 0.946 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 fraction boldt_WMM treiber_WMM | |
| DNAJC21 | MRPS18B | 0.988 | 0.052 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| MRPS28 | MRPS16 | 0.978 | 0.976 | bioplex_WMM bioplex3_WMM boldt boldt_WMM treiber_WMM WMM_only | |
| MRPS28 | DNAJC21 | 0.29 | 0.076 | bioplex_WMM bioplex3_WMM WMM_only | |
| DNAJC21 | MRPS16 | 0.279 | 0.044 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| MRPS28 | huMAP3_04135.1 huMAP3_05807.1 huMAP3_05954.1 |
| DNAJC21 | huMAP3_04135.1 huMAP3_05907.1 huMAP3_05962.1 huMAP3_06329.1 huMAP3_11914.1 |
| MRPS16 | huMAP3_04135.1 huMAP3_05807.1 huMAP3_05954.1 huMAP3_07050.1 |
| MRPS18B | huMAP3_04135.1 huMAP3_05807.1 huMAP3_05907.1 huMAP3_08562.1 |