hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_04142.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PGAM2 | Phosphoglycerate mutase 2 (EC 5.4.2.11) (EC 5.4.2.4) (BPG-dependent PGAM 2) (Muscle-specific phosphoglycerate mutase) (Phosphoglycerate mutase isozyme M) (PGAM-M) | 5 | UniProt NCBI |
| PGAM1 | Phosphoglycerate mutase 1 (EC 5.4.2.11) (EC 5.4.2.4) (BPG-dependent PGAM 1) (Phosphoglycerate mutase isozyme B) (PGAM-B) | 5 | UniProt NCBI |
| PGAM4 | Probable phosphoglycerate mutase 4 (EC 5.4.2.11) (EC 5.4.2.4) | 4 | UniProt NCBI |
| BPGM | Bisphosphoglycerate mutase (BPGM) (EC 5.4.2.4) (2,3-bisphosphoglycerate mutase, erythrocyte) (2,3-bisphosphoglycerate synthase) (EC 5.4.2.11) (2,3-diphosphoglycerate mutase) (DPGM) (BPG-dependent PGAM) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00260 | 2.85016817453e-07 | 1.0 | PGAM1 BPGM PGAM4 | Glycine, serine and threonine metabolism |
| KEGG:00010 | 1.97568475734e-06 | 1.0 | PGAM1 BPGM PGAM4 | Glycolysis / Gluconeogenesis |
| GO:0016868 | 8.07408345042e-06 | 1.0 | PGAM1 BPGM PGAM4 | intramolecular phosphotransferase activity |
| GO:0016866 | 0.000170228592746 | 1.0 | PGAM1 BPGM PGAM4 | intramolecular transferase activity |
| GO:0004082 | 0.00140460216025 | 0.666666666667 | PGAM1 BPGM | bisphosphoglycerate mutase activity |
| KEGG:01230 | 0.00168280767129 | 0.666666666667 | PGAM1 PGAM4 | Biosynthesis of amino acids |
| KEGG:05230 | 0.00168280767129 | 0.666666666667 | PGAM1 PGAM4 | Central carbon metabolism in cancer |
| KEGG:04922 | 0.00318234952896 | 0.666666666667 | PGAM1 PGAM4 | Glucagon signaling pathway |
| KEGG:01200 | 0.00406958776216 | 0.666666666667 | PGAM1 PGAM4 | Carbon metabolism |
| GO:0004619 | 0.00421361424067 | 0.666666666667 | PGAM1 PGAM4 | phosphoglycerate mutase activity |
| REAC:R-HSA-70171 | 0.0141416283812 | 0.666666666667 | PGAM1 BPGM | Glycolysis |
| KEGG:01100 | 0.0189521995452 | 1.0 | PGAM1 BPGM PGAM4 | Metabolic pathways |
| REAC:R-HSA-70326 | 0.0209338694285 | 0.666666666667 | PGAM1 BPGM | Glucose metabolism |
| GO:0016853 | 0.0225051619375 | 1.0 | PGAM1 BPGM PGAM4 | isomerase activity |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| PGAM2 | PGAM4 | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| PGAM1 | BPGM | 0.999 | 0.144 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| PGAM2 | PGAM1 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 | |
| PGAM1 | PGAM4 | 0.997 | 0.2 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only |
| PGAM4 | BPGM | 0.992 | 0.048 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| PGAM2 | BPGM | 0.986 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
Related Complexes
| Genename | Complexes |
|---|---|
| PGAM2 | huMAP3_04142.1 huMAP3_11712.1 huMAP3_11905.1 |
| PGAM1 | huMAP3_04142.1 huMAP3_11712.1 huMAP3_11905.1 |
| PGAM4 | huMAP3_04142.1 huMAP3_11712.1 huMAP3_11905.1 |
| BPGM | huMAP3_04142.1 huMAP3_11712.1 huMAP3_11905.1 |