hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_04143.1
Complex Portal: CPX-69
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CEBPA | CCAAT/enhancer-binding protein alpha (C/EBP alpha) | 5 | UniProt NCBI |
| DDIT3 | DNA damage-inducible transcript 3 protein (DDIT-3) (C/EBP zeta) (C/EBP-homologous protein) (CHOP) (C/EBP-homologous protein 10) (CHOP-10) (CCAAT/enhancer-binding protein homologous protein) (Growth arrest and DNA damage-inducible protein GADD153) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4211 | 2.34100360042e-05 | 1.0 | CEBPA DDIT3 | Transcriptional cascade regulating adipogenesis |
| WP:WP4149 | 0.000127691105477 | 1.0 | CEBPA DDIT3 | White fat cell differentiation |
| GO:0036488 | 0.00140460216025 | 1.0 | CEBPA DDIT3 | CHOP-C/EBP complex |
| KEGG:04932 | 0.00155920593969 | 1.0 | CEBPA DDIT3 | Non-alcoholic fatty liver disease |
| KEGG:05202 | 0.00194026930354 | 1.0 | CEBPA DDIT3 | Transcriptional misregulation in cancer |
| WP:WP236 | 0.00241378753054 | 1.0 | CEBPA DDIT3 | Adipogenesis |
| WP:WP4396 | 0.00396523446209 | 1.0 | CEBPA DDIT3 | Nonalcoholic fatty liver disease |
| CORUM:746 | 0.0249718442457 | 0.5 | CEBPA | C/EBPalpha-HNF6 complex |
| CORUM:5383 | 0.0499419797295 | 0.5 | DDIT3 | TRIB3-DDIT3 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| CEBPA | DDIT3 | 0.986 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes