hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_04148.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| AP3M1 | AP-3 complex subunit mu-1 (AP-3 adaptor complex mu3A subunit) (Adaptor-related protein complex 3 subunit mu-1) (Mu-adaptin 3A) (Mu3A-adaptin) | 5 | UniProt NCBI |
| AP3M2 | AP-3 complex subunit mu-2 (Adaptor-related protein complex 3 subunit mu-2) (Clathrin assembly protein assembly protein complex 3 mu-2 medium chain) (Clathrin coat assembly protein AP47 homolog 2) (Clathrin coat-associated protein AP47 homolog 2) (Golgi adaptor AP-1 47 kDa protein homolog 2) (HA1 47 kDa subunit homolog 2) (Mu3B-adaptin) (P47B) | 5 | UniProt NCBI |
| AP3S2 | AP-3 complex subunit sigma-2 (AP-3 complex subunit sigma-3B) (Adaptor-related protein complex 3 subunit sigma-2) (Sigma-3B-adaptin) (Sigma3B-adaptin) (Sigma-adaptin 3b) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:59 | 8.18540495785e-09 | 1.0 | AP3M1 AP3M2 AP3S2 | AP3 adaptor complex |
| CORUM:652 | 1.06410264452e-07 | 1.0 | AP3M1 AP3M2 AP3S2 | AP3-BLOC1 complex |
| GO:0035652 | 3.36420143768e-06 | 1.0 | AP3M1 AP3M2 AP3S2 | clathrin-coated vesicle cargo loading |
| GO:0035654 | 3.36420143768e-06 | 1.0 | AP3M1 AP3M2 AP3S2 | clathrin-coated vesicle cargo loading, AP-3-mediated |
| GO:0030123 | 8.07408345042e-06 | 1.0 | AP3M1 AP3M2 AP3S2 | AP-3 adaptor complex |
| KEGG:04142 | 1.58086646471e-05 | 1.0 | AP3M1 AP3M2 AP3S2 | Lysosome |
| GO:0099514 | 7.84339535184e-05 | 1.0 | AP3M1 AP3M2 AP3S2 | synaptic vesicle cytoskeletal transport |
| GO:0048490 | 7.84339535184e-05 | 1.0 | AP3M1 AP3M2 AP3S2 | anterograde synaptic vesicle transport |
| GO:0099517 | 7.84339535184e-05 | 1.0 | AP3M1 AP3M2 AP3S2 | synaptic vesicle transport along microtubule |
| GO:0035459 | 0.000432059584639 | 1.0 | AP3M1 AP3M2 AP3S2 | vesicle cargo loading |
| GO:0048489 | 0.000476755403739 | 1.0 | AP3M1 AP3M2 AP3S2 | synaptic vesicle transport |
| GO:0030119 | 0.000629105668845 | 1.0 | AP3M1 AP3M2 AP3S2 | AP-type membrane coat adaptor complex |
| GO:0097479 | 0.000746852719164 | 1.0 | AP3M1 AP3M2 AP3S2 | synaptic vesicle localization |
| GO:0047496 | 0.00102463963787 | 1.0 | AP3M1 AP3M2 AP3S2 | vesicle transport along microtubule |
| GO:0008089 | 0.00110345807156 | 1.0 | AP3M1 AP3M2 AP3S2 | anterograde axonal transport |
| GO:0098930 | 0.00238416149886 | 1.0 | AP3M1 AP3M2 AP3S2 | axonal transport |
| GO:0008088 | 0.00328922780564 | 1.0 | AP3M1 AP3M2 AP3S2 | axo-dendritic transport |
| GO:0099518 | 0.00381702295119 | 1.0 | AP3M1 AP3M2 AP3S2 | vesicle cytoskeletal trafficking |
| GO:0072384 | 0.00549374094772 | 1.0 | AP3M1 AP3M2 AP3S2 | organelle transport along microtubule |
| GO:0030117 | 0.0101882437539 | 1.0 | AP3M1 AP3M2 AP3S2 | membrane coat |
| GO:0048475 | 0.0101882437539 | 1.0 | AP3M1 AP3M2 AP3S2 | coated membrane |
| GO:0016183 | 0.0140440992017 | 0.666666666667 | AP3S2 AP3M2 | synaptic vesicle coating |
| GO:0016185 | 0.0294899169624 | 0.666666666667 | AP3S2 AP3M2 | synaptic vesicle budding from presynaptic endocytic zone membrane |
| GO:0070142 | 0.0294899169624 | 0.666666666667 | AP3S2 AP3M2 | synaptic vesicle budding |
| GO:0010970 | 0.039413061643 | 1.0 | AP3M1 AP3M2 AP3S2 | transport along microtubule |
| CORUM:2307 | 0.0499402709677 | 0.333333333333 | AP3S2 | AP3D1-AP3S2 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| AP3M2 | AP3M1 | 0.998 | 0.636 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM |
| AP3M1 | AP3S2 | 0.991 | 0.068 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM |
| AP3M2 | AP3S2 | 0.978 | 0.074 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes