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hu.MAP 3.0
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hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):
Enrichment (ex. cilium):
Protein (ex. Centrosomal protein):
Complex:
huMAP3_04150.1
Complex Portal:
CPX-24575
Confidence:
Extremely High
?
Proteins
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Genename
Protein Name
Uniprot Annotation Score
Links
LRRC8B
Volume-regulated anion channel subunit LRRC8B (Leucine-rich repeat-containing protein 8B) (T-cell activation leucine repeat-rich protein) (TA-LRRP)
5
UniProt
NCBI
LRRC8C
Volume-regulated anion channel subunit LRRC8C (Factor for adipocyte differentiation 158) (Leucine-rich repeat-containing protein 8C)
5
UniProt
NCBI
NPEPPS
Puromycin-sensitive aminopeptidase (PSA) (EC 3.4.11.14) (Cytosol alanyl aminopeptidase) (AAP-S)
5
UniProt
NCBI
Showing 1 to 3 of 3 entries
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Enrichments
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Term ID
Corrected Pval
Fraction Complex Coverage
Proteins
Term Name
CORUM:6567
3.41705576683e-05
0.666666666667
LRRC8C LRRC8B
SWELL1-containing complex
REAC:R-HSA-5223345
0.00129444299395
0.666666666667
LRRC8C LRRC8B
Miscellaneous transport and binding events
WP:WP5083
0.00688101165686
0.666666666667
LRRC8C LRRC8B
Neuroinflammation and glutamatergic signaling
CORUM:6581
0.0499402709677
0.333333333333
LRRC8C
LRRC8A-LRRC8C complex
Showing 1 to 4 of 4 entries
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Edges
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Protein 1
Protein 2
Score
?
ProteomeHD
?
Interface Overlap
?
Evidence
?
LRRC8C
LRRC8B
0.995
structurally_consistent (dimer)
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
NPEPPS
LRRC8B
0.983
structurally_consistent (Q8TDW0)
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
NPEPPS
LRRC8C
0.855
0.03
structurally_consistent (dimer)
bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only
Showing 1 to 3 of 3 entries
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Related Complexes
Genename
Complexes
LRRC8C
huMAP3_03130.1
huMAP3_04150.1
huMAP3_06870.1
huMAP3_07957.1
huMAP3_09876.1
huMAP3_09927.1
huMAP3_11805.1
huMAP3_13781.1
huMAP3_13909.1
LRRC8B
huMAP3_03130.1
huMAP3_04150.1
huMAP3_06870.1
huMAP3_07957.1
huMAP3_09876.1
huMAP3_09927.1
huMAP3_11805.1
huMAP3_13781.1
huMAP3_13909.1
NPEPPS
huMAP3_01211.1
huMAP3_02204.1
huMAP3_03130.1
huMAP3_04150.1
huMAP3_07957.1
huMAP3_09876.1
huMAP3_09927.1
huMAP3_11805.1
huMAP3_13781.1
huMAP3_13909.1