hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_04150.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| LRRC8C | Volume-regulated anion channel subunit LRRC8C (Factor for adipocyte differentiation 158) (Leucine-rich repeat-containing protein 8C) | 5 | UniProt NCBI |
| LRRC8B | Volume-regulated anion channel subunit LRRC8B (Leucine-rich repeat-containing protein 8B) (T-cell activation leucine repeat-rich protein) (TA-LRRP) | 5 | UniProt NCBI |
| NPEPPS | Puromycin-sensitive aminopeptidase (PSA) (EC 3.4.11.14) (Cytosol alanyl aminopeptidase) (AAP-S) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6567 | 3.41705576683e-05 | 0.666666666667 | LRRC8C LRRC8B | SWELL1-containing complex |
| REAC:R-HSA-5223345 | 0.00129444299395 | 0.666666666667 | LRRC8C LRRC8B | Miscellaneous transport and binding events |
| WP:WP5083 | 0.00688101165686 | 0.666666666667 | LRRC8C LRRC8B | Neuroinflammation and glutamatergic signaling |
| CORUM:6581 | 0.0499402709677 | 0.333333333333 | LRRC8C | LRRC8A-LRRC8C complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| LRRC8C | LRRC8B | 0.995 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| NPEPPS | LRRC8B | 0.983 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| NPEPPS | LRRC8C | 0.855 | 0.03 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only |
Related Complexes