hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_04177.1
Complex Portal: CPX-23993
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SORD | Sorbitol dehydrogenase (SDH) (EC 1.1.1.-) ((R,R)-butanediol dehydrogenase) (EC 1.1.1.4) (L-iditol 2-dehydrogenase) (EC 1.1.1.14) (Polyol dehydrogenase) (Ribitol dehydrogenase) (RDH) (EC 1.1.1.56) (Xylitol dehydrogenase) (XDH) (EC 1.1.1.9) | 5 | UniProt NCBI |
| RALA | Ras-related protein Ral-A (EC 3.6.5.2) | 5 | UniProt NCBI |
| CPM | Carboxypeptidase M (CPM) (EC 3.4.17.12) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP690 | 0.0181734005931 | 1.0 | SORD | Polyol pathway |
| REAC:R-HSA-5652227 | 0.0249718442456 | 1.0 | SORD | Fructose biosynthesis |
| KEGG:00040 | 0.0401542565921 | 1.0 | SORD | Pentose and glucuronate interconversions |
| HP:0033124 | 0.0495817777049 | 1.0 | SORD | Increased serum sorbitol concentration |
| REAC:R-HSA-5661270 | 0.0499436884912 | 1.0 | SORD | Formation of xylulose-5-phosphate |
| WP:WP5178 | 0.049976851631 | 1.0 | SORD | Disorders of fructose metabolism |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| RALA | CPM | 0.965 | 0.054 | hein_WMM bioplex3_WMM WMM_only | |
| SORD | CPM | 0.963 | 0.056 | hein_WMM bioplex3_WMM WMM_only | |
| RALA | SORD | 0.012 | 0.052 | bioplex3_WMM WMM_only |
Related Complexes