hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_04185.1
Confidence: Extremely High  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
IRGQ | Immunity-related GTPase family Q protein | 2 | UniProt   NCBI |
PNP | Purine nucleoside phosphorylase (PNP) (EC 2.4.2.1) (Inosine phosphorylase) (Inosine-guanosine phosphorylase) | 5 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  REAC:R-HSA-9735763 | 0.0249718442457 | 0.5 | PNP | Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine |
  REAC:R-HSA-9735786 | 0.0249718442457 | 0.5 | PNP | Nucleotide catabolism defects |
  CORUM:6208 | 0.0249718442457 | 0.5 | PNP | PNP homotrimer complex |
  HP:0032166 | 0.0499436884913 | 0.5 | PNP | Unusual gastrointestinal infection |
  HP:0033339 | 0.0499436884913 | 0.5 | PNP | Increased circulating inosine concentration |
  HP:0033340 | 0.0499436884913 | 0.5 | PNP | Increased circulating guanosine concentration |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
---|---|---|---|---|
 IRGQ |  PNP | 0.973 | 0.04           | hein_WMM     bioplex_WMM     bioplex3_WMM     WMM_only     |
Related Complexes
Genename | Complexes |
---|---|
IRGQ | huMAP3_04185.1 huMAP3_14510.1 huMAP3_14713.1 |
PNP | huMAP3_04185.1 |