hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_04208.1
Complex Portal: CPX-15657
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ATG16L2 | Protein Atg16l2 (APG16-like 2) (Autophagy-related protein 16-2) (WD repeat-containing protein 80) | 4 | UniProt NCBI |
| ATG5 | Autophagy protein 5 (APG5-like) (Apoptosis-specific protein) | 5 | UniProt NCBI |
| TECPR1 | Tectonin beta-propeller repeat-containing protein 1 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4863 | 0.000173183276299 | 0.666666666667 | ATG16L2 ATG5 | Host pathogen interaction of human coronaviruses autophagy |
| GO:0005776 | 0.00675723888767 | 1.0 | ATG16L2 ATG5 TECPR1 | autophagosome |
| KEGG:04140 | 0.00916431091176 | 0.666666666667 | ATG16L2 ATG5 | Autophagy - animal |
| KEGG:05131 | 0.0193802248568 | 0.666666666667 | TECPR1 ATG5 | Shigellosis |
| GO:0034274 | 0.0210651876021 | 0.666666666667 | ATG16L2 ATG5 | Atg12-Atg5-Atg16 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ATG5 | TECPR1 | 0.999 | 0.09 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only |
| ATG16L2 | ATG5 | 0.998 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| ATG16L2 | TECPR1 | 0.946 |
mutually_exclusive (Q9H1Y0)
|
bioplex3_WMM WMM_only |
Related Complexes