hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_04230.1
Complex Portal: CPX-11444
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CDH15 | Cadherin-15 (Cadherin-14) (Muscle cadherin) (M-cadherin) | 5 | UniProt NCBI |
| RTKN | Rhotekin | 5 | UniProt NCBI |
| TAX1BP3 | Tax1-binding protein 3 (Glutaminase-interacting protein 3) (Tax interaction protein 1) (TIP-1) (Tax-interacting protein 1) | 5 | UniProt NCBI |
| CIT | Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5666185 | 0.000368856835097 | 0.5 | RTKN TAX1BP3 | RHO GTPases Activate Rhotekin and Rhophilins |
| WP:WP524 | 0.0013446069671 | 0.5 | RTKN CIT | G13 signaling pathway |
| REAC:R-HSA-195258 | 0.00591360366085 | 0.75 | CIT RTKN TAX1BP3 | RHO GTPase Effectors |
| REAC:R-HSA-9013026 | 0.0186613511621 | 0.5 | RTKN CIT | RHOB GTPase cycle |
| REAC:R-HSA-9013106 | 0.0212029570934 | 0.5 | RTKN CIT | RHOC GTPase cycle |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| CDH15 | TAX1BP3 | 0.998 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| TAX1BP3 | CIT | 0.998 | 0.05 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| RTKN | TAX1BP3 | 0.987 | 0.088 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| CDH15 | CIT | 0.902 | bioplex3_WMM WMM_only | ||
| RTKN | CIT | 0.897 | 0.106 | bioplex3_WMM WMM_only | |
| RTKN | CDH15 | 0.881 | bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| CDH15 | huMAP3_04230.1 huMAP3_12107.1 huMAP3_13224.1 huMAP3_14504.1 |
| RTKN | huMAP3_03886.1 huMAP3_04230.1 huMAP3_12107.1 huMAP3_13224.1 huMAP3_13383.1 |
| TAX1BP3 | huMAP3_04230.1 huMAP3_12107.1 huMAP3_13927.1 huMAP3_14886.1 |
| CIT | huMAP3_04230.1 huMAP3_12107.1 huMAP3_13224.1 |