hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_04284.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PTGER3 | Prostaglandin E2 receptor EP3 subtype (PGE receptor EP3 subtype) (PGE2 receptor EP3 subtype) (PGE2-R) (Prostanoid EP3 receptor) | 5 | UniProt NCBI |
| PLEKHH3 | Pleckstrin homology domain-containing family H member 3 (PH domain-containing family H member 3) | 3 | UniProt NCBI |
| PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (EC 3.1.4.11) (PLC-154) (Phosphoinositide phospholipase C-beta-1) (Phospholipase C-I) (PLC-I) (Phospholipase C-beta-1) (PLC-beta-1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP5122 | 0.000261425039751 | 0.666666666667 | PLCB1 PTGER3 | Prostaglandin and leukotriene metabolism in senescence |
| WP:WP5321 | 0.00033946652894 | 0.666666666667 | PLCB1 PTGER3 | Prostaglandin and leukotriene metabolism in senescence |
| KEGG:04020 | 0.0111390641405 | 0.666666666667 | PLCB1 PTGER3 | Calcium signaling pathway |
| KEGG:05163 | 0.0138758373086 | 0.666666666667 | PLCB1 PTGER3 | Human cytomegalovirus infection |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| PLCB1 | PTGER3 | 0.99 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| PLEKHH3 | PTGER3 | 0.973 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| PLEKHH3 | PLCB1 | 0.342 | 0.102 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes