hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_04289.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TOMM5 | Mitochondrial import receptor subunit TOM5 homolog | 4 | UniProt NCBI |
| TOMM6 | Mitochondrial import receptor subunit TOM6 homolog (Overexpressed breast tumor protein) (Translocase of outer membrane 6 kDa subunit homolog) | 5 | UniProt NCBI |
| TOMM40L | Mitochondrial import receptor subunit TOM40B (Protein TOMM40-like) | 4 | UniProt NCBI |
| TOMM7 | Mitochondrial import receptor subunit TOM7 homolog (Translocase of outer membrane 7 kDa subunit homolog) | 5 | UniProt NCBI |
| TMEM125 | Transmembrane protein 125 | 2 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6497 | 9.80414034403e-08 | 0.6 | TOMM7 TOMM5 TOMM6 | TOM complex (TOM5, TOM6, TOM7, TOM20, TOM22, TOM40, TOM70), mitochondrial |
| REAC:R-HSA-5205685 | 4.14297217289e-06 | 0.6 | TOMM7 TOMM5 TOMM6 | PINK1-PRKN Mediated Mitophagy |
| REAC:R-HSA-5205647 | 8.09488316343e-06 | 0.6 | TOMM7 TOMM5 TOMM6 | Mitophagy |
| REAC:R-HSA-1268020 | 0.000106169184171 | 0.6 | TOMM7 TOMM5 TOMM6 | Mitochondrial protein import |
| REAC:R-HSA-9663891 | 0.000209176184702 | 0.6 | TOMM7 TOMM5 TOMM6 | Selective autophagy |
| GO:0045040 | 0.000349481973524 | 0.6 | TOMM7 TOMM5 TOMM6 | protein insertion into mitochondrial outer membrane |
| GO:0007008 | 0.000349481973524 | 0.6 | TOMM7 TOMM5 TOMM6 | outer mitochondrial membrane organization |
| GO:0006626 | 0.000349949920328 | 0.8 | TOMM7 TOMM5 TOMM40L TOMM6 | protein targeting to mitochondrion |
| GO:0072655 | 0.000534309588813 | 0.8 | TOMM7 TOMM5 TOMM40L TOMM6 | establishment of protein localization to mitochondrion |
| GO:0070585 | 0.000649914918254 | 0.8 | TOMM7 TOMM5 TOMM40L TOMM6 | protein localization to mitochondrion |
| REAC:R-HSA-1632852 | 0.00100303062327 | 0.6 | TOMM7 TOMM5 TOMM6 | Macroautophagy |
| GO:0005742 | 0.00109385703544 | 0.6 | TOMM7 TOMM5 TOMM40L | mitochondrial outer membrane translocase complex |
| REAC:R-HSA-9609507 | 0.0012622367962 | 0.6 | TOMM7 TOMM5 TOMM6 | Protein localization |
| GO:0098799 | 0.00127603542925 | 0.6 | TOMM7 TOMM5 TOMM40L | outer mitochondrial membrane protein complex |
| REAC:R-HSA-9612973 | 0.00140702215103 | 0.6 | TOMM7 TOMM5 TOMM6 | Autophagy |
| GO:0006839 | 0.00211972422452 | 0.8 | TOMM7 TOMM5 TOMM40L TOMM6 | mitochondrial transport |
| GO:0005741 | 0.00326030759216 | 0.8 | TOMM7 TOMM5 TOMM40L TOMM6 | mitochondrial outer membrane |
| GO:0090151 | 0.00350285844735 | 0.6 | TOMM7 TOMM5 TOMM6 | establishment of protein localization to mitochondrial membrane |
| GO:0031968 | 0.00480818953079 | 0.8 | TOMM7 TOMM5 TOMM40L TOMM6 | organelle outer membrane |
| GO:0019867 | 0.00492038984684 | 0.8 | TOMM7 TOMM5 TOMM40L TOMM6 | outer membrane |
| GO:0006605 | 0.019016548402 | 0.8 | TOMM7 TOMM5 TOMM40L TOMM6 | protein targeting |
| KEGG:04137 | 0.0213229262457 | 0.4 | TOMM7 TOMM40L | Mitophagy - animal |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| TOMM6 | TMEM125 | 0.984 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| TOMM6 | TOMM40L | 0.984 | 0.142 | bioplex3_HEK293 bioplex3_WMM WMM_only |
| TOMM6 | TOMM5 | 0.982 | 0.744 | bioplex3_HEK293 bioplex3_WMM WMM_only |
| TOMM7 | TOMM6 | 0.97 | 0.5 | bioplex3_HEK293 bioplex3_WMM WMM_only |
| TOMM7 | TOMM40L | 0.707 | 0.126177606178 | bioplex3_HEK293 bioplex3_WMM WMM_only |
| TOMM7 | TMEM125 | 0.415 | bioplex3_WMM WMM_only | |
| TMEM125 | TOMM5 | 0.415 | bioplex3_WMM WMM_only | |
| TOMM40L | TMEM125 | 0.415 | bioplex3_WMM WMM_only | |
| TOMM7 | TOMM5 | 0.415 | 0.85 | bioplex3_WMM WMM_only |
| TOMM40L | TOMM5 | 0.274 | 0.04 | bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| TOMM5 | huMAP3_04289.1 huMAP3_05595.1 huMAP3_10390.1 huMAP3_13692.1 |
| TOMM6 | huMAP3_01133.1 huMAP3_04289.1 huMAP3_05595.1 huMAP3_13692.1 |
| TOMM40L | huMAP3_01133.1 huMAP3_04289.1 |
| TOMM7 | huMAP3_01133.1 huMAP3_04289.1 huMAP3_13692.1 |
| TMEM125 | huMAP3_01133.1 huMAP3_04289.1 huMAP3_13692.1 |