hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_04290.1
Confidence: Extremely High  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
ACLY | ATP-citrate synthase (EC 2.3.3.8) (ATP-citrate (pro-S-)-lyase) (ACL) (Citrate cleavage enzyme) | 5 | UniProt   NCBI |
GSR | Glutathione reductase, mitochondrial (GR) (GRase) (EC 1.8.1.7) | 5 | UniProt   NCBI |
GPX7 | Glutathione peroxidase 7 (GPx-7) (GSHPx-7) (EC 1.11.1.9) (CL683) | 5 | UniProt   NCBI |
THYN1 | Thymocyte nuclear protein 1 (Thymocyte protein Thy28) | 3 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  WP:WP3940 | 0.0022974831852 | 0.5 | GSR GPX7 | One carbon metabolism and related pathways |
  KEGG:00480 | 0.0030591266514 | 0.5 | GSR GPX7 | Glutathione metabolism |
  WP:WP2525 | 0.00377411060353 | 0.5 | GSR GPX7 | Trans sulfuration one carbon metabolism and related pathways |
  KEGG:04918 | 0.00441608599796 | 0.5 | GSR GPX7 | Thyroid hormone synthesis |
  WP:WP3925 | 0.00862655865142 | 0.5 | ACLY GSR | Amino acid metabolism |
  WP:WP2366 | 0.0248784837172 | 0.25 | ACLY | Butyrate induced histone acetylation |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
---|---|---|---|---|
 GSR |  GPX7 | 0.984 | 0.238           | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116     |
 ACLY |  GPX7 | 0.97 | 0.056           | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116     |
 GPX7 |  THYN1 | 0.96 | 0.056           | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     |
 GSR |  THYN1 | 0.043 | 0.054           | bioplex_WMM     bioplex3_WMM     WMM_only     |
 ACLY |  THYN1 | 0.037 | 0.014           | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     |
 ACLY |  GSR | 0.034 | 0.102           | bioplex_WMM     bioplex3_WMM     gupta_WMM     fraction     |
Related Complexes
Genename | Complexes |
---|---|
ACLY | huMAP3_04290.1 huMAP3_11255.1 huMAP3_11508.1 huMAP3_14058.1 huMAP3_14536.1 huMAP3_14551.1 |
GSR | huMAP3_04290.1 huMAP3_12401.1 huMAP3_13322.1 huMAP3_14033.1 huMAP3_14359.1 |
GPX7 | huMAP3_04290.1 huMAP3_11363.1 |
THYN1 | huMAP3_04290.1 huMAP3_11363.1 |