hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_04347.1
Complex Portal: CPX-21347
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MBTPS2 | Membrane-bound transcription factor site-2 protease (EC 3.4.24.85) (Endopeptidase S2P) (Sterol regulatory element-binding proteins intramembrane protease) (SREBPs intramembrane protease) | 5 | UniProt NCBI |
| OR6T1 | Olfactory receptor 6T1 (Olfactory receptor OR11-277) | 3 | UniProt NCBI |
| IL17RC | Interleukin-17 receptor C (IL-17 receptor C) (IL-17RC) (Interleukin-17 receptor homolog) (IL17Rhom) (Interleukin-17 receptor-like protein) (IL-17RL) (ZcytoR14) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0100825 | 0.0125029572242 | 0.666666666667 | IL17RC MBTPS2 | Cheilitis |
| WP:WP5256 | 0.0331010360575 | 0.333333333333 | IL17RC | COVID 19 and endothelial cell senescence |
| HP:0200034 | 0.0388502441646 | 0.666666666667 | IL17RC MBTPS2 | Papule |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| MBTPS2 | IL17RC | 0.993 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| MBTPS2 | OR6T1 | 0.983 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes