hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_04357.1
Complex Portal: CPX-12490
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ANGPT4 | Angiopoietin-4 (ANG-4) (Angiopoietin-3) (ANG-3) | 5 | UniProt NCBI |
| ANGPT1 | Angiopoietin-1 (ANG-1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-210993 | 0.000179419983974 | 1.0 | ANGPT4 ANGPT1 | Tie2 Signaling |
| KEGG:04066 | 0.00078862558789 | 1.0 | ANGPT4 ANGPT1 | HIF-1 signaling pathway |
| WP:WP3303 | 0.000831269096657 | 1.0 | ANGPT4 ANGPT1 | RAC1 PAK1 p38 MMP2 pathway |
| KEGG:04015 | 0.00222639196581 | 1.0 | ANGPT4 ANGPT1 | Rap1 signaling pathway |
| KEGG:04014 | 0.00273702337615 | 1.0 | ANGPT4 ANGPT1 | Ras signaling pathway |
| KEGG:04010 | 0.0047800367266 | 1.0 | ANGPT4 ANGPT1 | MAPK signaling pathway |
| KEGG:04151 | 0.00662552789826 | 1.0 | ANGPT4 ANGPT1 | PI3K-Akt signaling pathway |
| REAC:R-HSA-202733 | 0.00880183178522 | 1.0 | ANGPT4 ANGPT1 | Cell surface interactions at the vascular wall |
| WP:WP3932 | 0.0130364105952 | 1.0 | ANGPT4 ANGPT1 | Focal adhesion PI3K Akt mTOR signaling pathway |
| WP:WP4172 | 0.015571930313 | 1.0 | ANGPT4 ANGPT1 | PI3K Akt signaling pathway |
| WP:WP5087 | 0.0293715080819 | 1.0 | ANGPT4 ANGPT1 | Pleural mesothelioma |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ANGPT4 | ANGPT1 | 0.981 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| ANGPT4 | huMAP3_04357.1 huMAP3_11248.1 huMAP3_14821.1 |
| ANGPT1 | huMAP3_04357.1 huMAP3_11248.1 huMAP3_14821.1 |