hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_04371.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| VAV2 | Guanine nucleotide exchange factor VAV2 (VAV-2) | 5 | UniProt NCBI |
| SHC2 | SHC-transforming protein 2 (Protein Sck) (SHC-transforming protein B) (Src homology 2 domain-containing-transforming protein C2) (SH2 domain protein C2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04650 | 0.00095688522167 | 1.0 | VAV2 SHC2 | Natural killer cell mediated cytotoxicity |
| KEGG:04062 | 0.00155920593969 | 1.0 | VAV2 SHC2 | Chemokine signaling pathway |
| KEGG:04510 | 0.00241871191437 | 1.0 | VAV2 SHC2 | Focal adhesion |
| WP:WP3929 | 0.00309012475255 | 1.0 | VAV2 SHC2 | Chemokine signaling pathway |
| WP:WP2380 | 0.00319355454799 | 1.0 | VAV2 SHC2 | Brain derived neurotrophic factor BDNF signaling pathway |
| WP:WP306 | 0.00633262755764 | 1.0 | VAV2 SHC2 | Focal adhesion |
| REAC:R-HSA-4420097 | 0.00639247771471 | 1.0 | VAV2 SHC2 | VEGFA-VEGFR2 Pathway |
| REAC:R-HSA-194138 | 0.00762962122326 | 1.0 | VAV2 SHC2 | Signaling by VEGF |
| WP:WP3888 | 0.0309740314556 | 1.0 | VAV2 SHC2 | VEGFA VEGFR2 signaling |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| VAV2 | SHC2 | 0.973 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes