hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_04416.1

Complex Portal: CPX-11783

Confidence: Extremely High

Genename	Protein Name	Uniprot Annotation Score	Links
ANKRD29	Ankyrin repeat domain-containing protein 29	4	UniProt NCBI
ADD3	Gamma-adducin (Adducin-like protein 70)	5	UniProt NCBI
ADD1	Alpha-adducin (Erythrocyte adducin subunit alpha)	5	UniProt NCBI
ADD2	Beta-adducin (Erythrocyte adducin subunit beta)	5	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-5223345	1.59826617962e-06	0.75	ADD3 ADD2 ADD1	Miscellaneous transport and binding events
GO:0051016	0.000591522022343	0.75	ADD3 ADD2 ADD1	barbed-end actin filament capping
GO:0051693	0.000591522022343	0.75	ADD3 ADD2 ADD1	actin filament capping
GO:0030835	0.000883305813556	0.75	ADD3 ADD2 ADD1	negative regulation of actin filament depolymerization
GO:0030834	0.00190418300832	0.75	ADD3 ADD2 ADD1	regulation of actin filament depolymerization
GO:0030042	0.00298219742351	0.75	ADD3 ADD2 ADD1	actin filament depolymerization
GO:0030837	0.00298219742351	0.75	ADD3 ADD2 ADD1	negative regulation of actin filament polymerization
GO:1901880	0.00544401218013	0.75	ADD3 ADD2 ADD1	negative regulation of protein depolymerization
GO:0032272	0.00663460918661	0.75	ADD3 ADD2 ADD1	negative regulation of protein polymerization
GO:0043242	0.0100599149475	0.75	ADD3 ADD2 ADD1	negative regulation of protein-containing complex disassembly
GO:1901879	0.0106287970558	0.75	ADD3 ADD2 ADD1	regulation of protein depolymerization
GO:0030833	0.0258660780327	0.75	ADD3 ADD2 ADD1	regulation of actin filament polymerization
GO:0051261	0.0339114962397	0.75	ADD3 ADD2 ADD1	protein depolymerization
REAC:R-HSA-382551	0.0342552713859	0.75	ADD3 ADD2 ADD1	Transport of small molecules
GO:0008064	0.0420072408269	0.75	ADD3 ADD2 ADD1	regulation of actin polymerization or depolymerization
GO:0043244	0.0434703685672	0.75	ADD3 ADD2 ADD1	regulation of protein-containing complex disassembly
GO:0030832	0.0464975978221	0.75	ADD3 ADD2 ADD1	regulation of actin filament length
CORUM:6287	0.049938562206	0.25	ADD2	SLC2A1-DMTN-ADD2 complex

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap	Evidence
ADD1	ADD2	1.0	0.352		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM
ANKRD29	ADD2	1.0			bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
ANKRD29	ADD3	0.999			bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
ADD3	ADD1	0.999	0.558		hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only
ANKRD29	ADD1	0.999			bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
ADD3	ADD2	0.999	0.106		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM

Related Complexes

Genename	Complexes
ANKRD29	huMAP3_04416.1 huMAP3_05945.1 huMAP3_06824.1 huMAP3_08197.1 huMAP3_09356.1 huMAP3_11374.1 huMAP3_12960.1 huMAP3_14427.1 huMAP3_15156.1
ADD3	huMAP3_04416.1 huMAP3_05945.1 huMAP3_06824.1
ADD1	huMAP3_04416.1 huMAP3_05945.1 huMAP3_06824.1 huMAP3_08371.1 huMAP3_14427.1
ADD2	huMAP3_04416.1 huMAP3_06824.1 huMAP3_11374.1 huMAP3_12960.1 huMAP3_14427.1