hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_04429.1
Complex Portal: CPX-22737
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| EPN3 | Epsin-3 (EPS-15-interacting protein 3) | 5 | UniProt NCBI |
| PHGDH | D-3-phosphoglycerate dehydrogenase (3-PGDH) (EC 1.1.1.95) (2-oxoglutarate reductase) (EC 1.1.1.399) (Malate dehydrogenase) (EC 1.1.1.37) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP5213 | 0.0373151717536 | 0.5 | PHGDH | Amino acid metabolism in triple negative breast cancer cells |
| WP:WP4688 | 0.0435328773163 | 0.5 | PHGDH | Serine metabolism |
| HP:0007525 | 0.0499436884913 | 0.5 | PHGDH | Yellow subcutaneous tissue covered by thin, scaly skin |
| HP:0012277 | 0.0499436884913 | 0.5 | PHGDH | Hypoglycinemia |
| HP:0034691 | 0.0499436884913 | 0.5 | PHGDH | Reduced 3-phosphoglycerate dehydrogenase activity |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| EPN3 | PHGDH | 0.999 | 0.02 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM |
Related Complexes