hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_04452.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| LYN | Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn) | 5 | UniProt NCBI |
| GPRC5A | Retinoic acid-induced protein 3 (G-protein coupled receptor family C group 5 member A) (Phorbol ester induced gene 1) (PEIG-1) (Retinoic acid-induced gene 1 protein) (RAIG-1) | 5 | UniProt NCBI |
| NF2 | Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomerlin) (Schwannomin) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-2029480 | 0.0204048321881 | 0.666666666667 | LYN NF2 | Fcgamma receptor (FCGR) dependent phagocytosis |
| CORUM:2910 | 0.0249718442456 | 0.333333333333 | LYN | PLC-gamma-2-Lyn-FcR-gamma complex |
| GO:0050730 | 0.0402954436201 | 1.0 | LYN NF2 GPRC5A | regulation of peptidyl-tyrosine phosphorylation |
| CORUM:2536 | 0.0499402709677 | 0.333333333333 | LYN | PLC-gamma-2-SLP-76-Lyn-Grb2 complex |
| CORUM:6617 | 0.0499402709677 | 0.333333333333 | NF2 | NF2-WWC1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| LYN | NF2 | 0.967 | 0.06 | hein_WMM bioplex_WMM bioplex3_WMM gupta_WMM WMM_only |
| GPRC5A | LYN | 0.95 | 0.072 | hein_WMM bioplex3_WMM gupta_WMM WMM_only |
| GPRC5A | NF2 | 0.942 | 0.012 | hein_WMM gupta_WMM WMM_only |
Related Complexes