hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_04483.1
Complex Portal: CPX-21590
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| LAMA4 | Laminin subunit alpha-4 (Laminin-14 subunit alpha) (Laminin-8 subunit alpha) (Laminin-9 subunit alpha) | 5 | UniProt NCBI |
| NID2 | Nidogen-2 (NID-2) (Osteonidogen) | 5 | UniProt NCBI |
| PPIB | Peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (CYP-S1) (Cyclophilin B) (Rotamase B) (S-cyclophilin) (SCYLP) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-3000157 | 0.000599775374997 | 1.0 | NID2 LAMA4 | Laminin interactions |
| REAC:R-HSA-1474244 | 0.0442193366216 | 1.0 | NID2 LAMA4 | Extracellular matrix organization |
| CORUM:2374 | 0.0499419797295 | 0.5 | LAMA4 | ITGAV-ITGB3-LAMA4 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| LAMA4 | NID2 | 0.988 | 0.264 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| PPIB | NID2 | 0.973 | 0.168 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PPIB | LAMA4 | 0.059 | 0.156 | bioplex3_WMM WMM_only |
Related Complexes