hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_04496.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GPAA1 | Glycosylphosphatidylinositol anchor attachment 1 protein (GPI anchor attachment protein 1) (GAA1 protein homolog) (hGAA1) | 5 | UniProt NCBI |
| PIGU | Phosphatidylinositol glycan anchor biosynthesis class U protein (Cell division cycle protein 91-like 1) (Protein CDC91-like 1) (GPI transamidase component PIG-U) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:994 | 1.70876175213e-05 | 1.0 | PIGU GPAA1 | GAA1-GPI8-PIGT-PIG-PIGS complex |
| KEGG:00563 | 3.41396358394e-05 | 1.0 | PIGU GPAA1 | Glycosylphosphatidylinositol (GPI)-anchor biosynthesis |
| REAC:R-HSA-162791 | 3.58839967947e-05 | 1.0 | PIGU GPAA1 | Attachment of GPI anchor to uPAR |
| REAC:R-HSA-163125 | 0.00355422444443 | 1.0 | PIGU GPAA1 | Post-translational modification: synthesis of GPI-anchored proteins |
| GO:0042765 | 0.00468200720083 | 1.0 | PIGU GPAA1 | GPI-anchor transamidase complex |
| GO:0016255 | 0.00702301080125 | 1.0 | PIGU GPAA1 | attachment of GPI anchor to protein |
| HP:0003155 | 0.0102628230833 | 1.0 | PIGU GPAA1 | Elevated circulating alkaline phosphatase concentration |
| HP:0004379 | 0.0127849554294 | 1.0 | PIGU GPAA1 | Abnormality of alkaline phosphatase level |
| GO:0034235 | 0.0131096201623 | 1.0 | PIGU GPAA1 | GPI anchor binding |
| GO:0008303 | 0.016855225923 | 1.0 | PIGU GPAA1 | caspase complex |
| HP:0000341 | 0.0392194997349 | 1.0 | PIGU GPAA1 | Narrow forehead |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| GPAA1 | PIGU | 0.998 | 0.07 |
structurally_consistent (dimer)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt gupta_WMM boldt_WMM |
Related Complexes