hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_04506.1
Complex Portal: CPX-22883
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| RELL1 | RELT-like protein 1 | 5 | UniProt NCBI |
| STK39 | STE20/SPS1-related proline-alanine-rich protein kinase (Ste-20-related kinase) (EC 2.7.11.1) (DCHT) (Serine/threonine-protein kinase 39) | 5 | UniProt NCBI |
| OXSR1 | Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress-responsive 1 protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0003096 | 0.0140440992017 | 0.666666666667 | STK39 OXSR1 | renal sodium ion transport |
| GO:0038146 | 0.0140440992017 | 0.666666666667 | STK39 OXSR1 | chemokine (C-X-C motif) ligand 12 signaling pathway |
| GO:0070294 | 0.0140440992017 | 0.666666666667 | STK39 OXSR1 | renal sodium ion absorption |
| HPA:0600433 | 0.0311676675212 | 1.0 | RELL1 OXSR1 STK39 | tonsil; germinal center cells[High] |
| CORUM:1121 | 0.0499402709677 | 0.333333333333 | OXSR1 | WNK1-OSR1 complex |
| CORUM:1123 | 0.0499402709677 | 0.333333333333 | STK39 | WNK1-SPAK complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| RELL1 | OXSR1 | 0.992 | 0.062 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| STK39 | OXSR1 | 0.979 | 0.198 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| RELL1 | STK39 | 0.966 | 0.05 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes
| Genename | Complexes |
|---|---|
| RELL1 | huMAP3_01293.1 huMAP3_04506.1 huMAP3_08598.1 huMAP3_11773.1 huMAP3_14637.1 |
| STK39 | huMAP3_01293.1 huMAP3_04506.1 huMAP3_08598.1 huMAP3_14637.1 |
| OXSR1 | huMAP3_01293.1 huMAP3_04506.1 huMAP3_08598.1 huMAP3_14456.1 huMAP3_14637.1 |