hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_04511.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ZNF669 | Zinc finger protein 669 | 5 | UniProt NCBI |
| CUL7 | Cullin-7 (CUL-7) | 5 | UniProt NCBI |
| FBXW8 | F-box/WD repeat-containing protein 8 (F-box and WD-40 domain-containing protein 8) (F-box only protein 29) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:81 | 2.05032700758e-05 | 0.666666666667 | CUL7 FBXW8 | Ubiquitin E3 ligase (SKP1A, FBXW8, CUL7, RBX1) |
| CORUM:6577 | 7.17516227795e-05 | 0.666666666667 | CUL7 FBXW8 | 3M complex |
| KEGG:04120 | 0.00686279305854 | 0.666666666667 | CUL7 FBXW8 | Ubiquitin mediated proteolysis |
| GO:0031467 | 0.00842684400117 | 0.666666666667 | CUL7 FBXW8 | Cul7-RING ubiquitin ligase complex |
| GO:1990393 | 0.0140440992017 | 0.666666666667 | CUL7 FBXW8 | 3M complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| FBXW8 | ZNF669 | 0.985 | 0.092 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| CUL7 | FBXW8 | 0.965 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| CUL7 | ZNF669 | 0.957 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes