hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_04529.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ACTR3B | Actin-related protein 3B (ARP3-beta) (Actin-like protein 3B) (Actin-related protein ARP4) | 4 | UniProt NCBI |
| CHURC1 | Protein Churchill | 4 | UniProt NCBI |
| ACTR2 | Actin-related protein 2 (Actin-like protein 2) | 5 | UniProt NCBI |
| ARPC1A | Actin-related protein 2/3 complex subunit 1A (SOP2-like protein) | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:05100 | 2.40425716137e-05 | 0.75 | ACTR3B ARPC1A ACTR2 | Bacterial invasion of epithelial cells |
| KEGG:04666 | 4.01491324891e-05 | 0.75 | ACTR3B ARPC1A ACTR2 | Fc gamma R-mediated phagocytosis |
| KEGG:05135 | 8.42717414951e-05 | 0.75 | ACTR3B ARPC1A ACTR2 | Yersinia infection |
| KEGG:04530 | 0.000149305865271 | 0.75 | ACTR3B ARPC1A ACTR2 | Tight junction |
| KEGG:05130 | 0.000250261342721 | 0.75 | ACTR3B ARPC1A ACTR2 | Pathogenic Escherichia coli infection |
| KEGG:04810 | 0.000413615830979 | 0.75 | ACTR3B ARPC1A ACTR2 | Regulation of actin cytoskeleton |
| KEGG:05132 | 0.000627272119201 | 0.75 | ACTR3B ARPC1A ACTR2 | Salmonella infection |
| KEGG:05131 | 0.000652828786911 | 0.75 | ACTR3B ARPC1A ACTR2 | Shigellosis |
| KEGG:04144 | 0.000687966939719 | 0.75 | ACTR3B ARPC1A ACTR2 | Endocytosis |
| REAC:R-HSA-5663213 | 0.00573491177379 | 0.5 | ACTR2 ARPC1A | RHO GTPases Activate WASPs and WAVEs |
| REAC:R-HSA-3928662 | 0.00718390333861 | 0.5 | ACTR2 ARPC1A | EPHB-mediated forward signaling |
| REAC:R-HSA-9664422 | 0.0140623832262 | 0.5 | ACTR2 ARPC1A | FCGR3A-mediated phagocytosis |
| REAC:R-HSA-9664417 | 0.0140623832262 | 0.5 | ACTR2 ARPC1A | Leishmania phagocytosis |
| REAC:R-HSA-9664407 | 0.0140623832262 | 0.5 | ACTR2 ARPC1A | Parasite infection |
| REAC:R-HSA-2029482 | 0.0157112703152 | 0.5 | ACTR2 ARPC1A | Regulation of actin dynamics for phagocytic cup formation |
| REAC:R-HSA-2029480 | 0.0305753786405 | 0.5 | ACTR2 ARPC1A | Fcgamma receptor (FCGR) dependent phagocytosis |
| REAC:R-HSA-2682334 | 0.0338007536087 | 0.5 | ACTR2 ARPC1A | EPH-Ephrin signaling |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| ACTR2 | ARPC1A | 1.0 | 0.524 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM hein () bioplex3_HCT116 gupta_WMM fraction |
| ACTR3B | ARPC1A | 0.999 | 0.184714893617 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| ACTR3B | ACTR2 | 0.999 | 0.884 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 |
| ACTR3B | CHURC1 | 0.998 | 0.158 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| CHURC1 | ACTR2 | 0.997 | 0.114 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116 |
| CHURC1 | ARPC1A | 0.772 | 0.082 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes