hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_04564.1
Complex Portal: CPX-24837
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| FGF2 | Fibroblast growth factor 2 (FGF-2) (Basic fibroblast growth factor) (bFGF) (Heparin-binding growth factor 2) (HBGF-2) | 5 | UniProt NCBI |
| IL7R | Interleukin-7 receptor subunit alpha (IL-7 receptor subunit alpha) (IL-7R subunit alpha) (IL-7R-alpha) (IL-7RA) (CDw127) (CD antigen CD127) | 5 | UniProt NCBI |
| GMEB2 | Glucocorticoid modulatory element-binding protein 2 (GMEB-2) (DNA-binding protein p79PIF) (Parvovirus initiation factor p79) (PIF p79) | 5 | UniProt NCBI |
| GMEB1 | Glucocorticoid modulatory element-binding protein 1 (GMEB-1) (DNA-binding protein p96PIF) (Parvovirus initiation factor p96) (PIF p96) | 5 | UniProt NCBI |
| PRDM10 | PR domain zinc finger protein 10 (EC 2.1.1.-) (PR domain-containing protein 10) (Tristanin) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HPA:0340462 | 0.0206302734533 | 1.0 | FGF2 PRDM10 GMEB2 GMEB1 | ovary; ovarian stroma cells[>=Medium] |
| CORUM:1069 | 0.049938562206 | 0.25 | FGF2 | FIF-FGR2 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| GMEB2 | GMEB1 | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 boldt_WMM | ||
| FGF2 | GMEB2 | 0.992 | 0.104 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM | |
| FGF2 | GMEB1 | 0.992 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM | ||
| FGF2 | IL7R | 0.985 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| FGF2 | PRDM10 | 0.976 | 0.076 | bioplex_WMM bioplex3_WMM WMM_only | |
| IL7R | GMEB1 | 0.92 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| IL7R | GMEB2 | 0.881 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| GMEB2 | PRDM10 | 0.834 | 0.166 | bioplex_WMM bioplex3_WMM WMM_only | |
| IL7R | PRDM10 | 0.616 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| GMEB1 | PRDM10 | 0.601 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes